Type-2 CD8(+) T-cell formation relies on interleukin-33 and is linked to asthma exacerbations

CD4(+) T helper 2 (Th2) cells and group 2 innate lymphoid cells are considered the main producers of type-2 cytokines that fuel chronic airway inflammation in allergic asthma. However, CD8(+) cytotoxic T (Tc) cells - critical for anti-viral defense - can also produce type-2 cytokines (referred to as...

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Detalles Bibliográficos
Autores principales: van der Ploeg, Esmee K., Krabbendam, Lisette, Vroman, Heleen, van Nimwegen, Menno, de Bruijn, Marjolein J. W., de Boer, Geertje M., Bergen, Ingrid M., Kool, Mirjam, Tramper-Standers, Gerdien A., Braunstahl, Gert-Jan, Huylebroeck, Danny, Hendriks, Rudi W., Stadhouders, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447424/
https://www.ncbi.nlm.nih.gov/pubmed/37612281
http://dx.doi.org/10.1038/s41467-023-40820-x

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