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Robust electrocardiogram delineation model for automatic morphological abnormality interpretation

Knowledge of electrocardiogram (ECG) wave signals is one of the essential steps in diagnosing heart abnormalities. Considerable performance with respect to obtaining the critical point of a signal waveform (P-QRS-T) through ECG delineation has been achieved in many studies. However, several deficien...

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Autores principales: Nurmaini, Siti, Darmawahyuni, Annisa, Rachmatullah, Muhammad Naufal, Firdaus, Firdaus, Sapitri, Ade Iriani, Tutuko, Bambang, Tondas, Alexander Edo, Putra, Muhammad Hafizh Permana, Islami, Anggun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447439/
https://www.ncbi.nlm.nih.gov/pubmed/37612382
http://dx.doi.org/10.1038/s41598-023-40965-1
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author Nurmaini, Siti
Darmawahyuni, Annisa
Rachmatullah, Muhammad Naufal
Firdaus, Firdaus
Sapitri, Ade Iriani
Tutuko, Bambang
Tondas, Alexander Edo
Putra, Muhammad Hafizh Permana
Islami, Anggun
author_facet Nurmaini, Siti
Darmawahyuni, Annisa
Rachmatullah, Muhammad Naufal
Firdaus, Firdaus
Sapitri, Ade Iriani
Tutuko, Bambang
Tondas, Alexander Edo
Putra, Muhammad Hafizh Permana
Islami, Anggun
author_sort Nurmaini, Siti
collection PubMed
description Knowledge of electrocardiogram (ECG) wave signals is one of the essential steps in diagnosing heart abnormalities. Considerable performance with respect to obtaining the critical point of a signal waveform (P-QRS-T) through ECG delineation has been achieved in many studies. However, several deficiencies remain regarding previous methods, including the effects of noise interference on the performance degradation of delineation and the role of medical knowledge in reaching a delineation decision. To address these challenges, this paper proposes a robust delineation model based on a convolutional recurrent network with grid search optimization, aiming to classify the precise P-QRS-T waves. In order to make a delineation decision, the results from the ECG waveform classification model are utilized to interpret morphological abnormalities, based on medical knowledge. We generated 36 models, and the model with the best results achieved 99.97% accuracy, 99.92% sensitivity, and 99.93% precision for ECG waveform classification (P-wave, QRS-complex, T-wave, and isoelectric line class). To ensure the model robustness, we evaluated delineation model performance on seven different types of ECG datasets, namely the Lobachevsky University Electrocardiography Database (LUDB), QT Database (QTDB), the PhysioNet/Computing in Cardiology Challenge 2017, China Physiological Signal Challenge 2018, ECG Arrhythmia of Chapman University, MIT-BIH Arrhythmia Database and General Mohammad Hossein Hospital (Indonesia) databases. To detect the patterns of ECG morphological abnormalities through proposed delineation model, we focus on investigating arrhythmias. This process is based on two inputs examination: the P-wave and the regular/irregular rhythm of the RR interval. As the results, the proposed method has considerable capability to interpret the delineation result in cases with artifact noise, baseline drift and abnormal morphologies for delivering robust ECG delineation.
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spelling pubmed-104474392023-08-25 Robust electrocardiogram delineation model for automatic morphological abnormality interpretation Nurmaini, Siti Darmawahyuni, Annisa Rachmatullah, Muhammad Naufal Firdaus, Firdaus Sapitri, Ade Iriani Tutuko, Bambang Tondas, Alexander Edo Putra, Muhammad Hafizh Permana Islami, Anggun Sci Rep Article Knowledge of electrocardiogram (ECG) wave signals is one of the essential steps in diagnosing heart abnormalities. Considerable performance with respect to obtaining the critical point of a signal waveform (P-QRS-T) through ECG delineation has been achieved in many studies. However, several deficiencies remain regarding previous methods, including the effects of noise interference on the performance degradation of delineation and the role of medical knowledge in reaching a delineation decision. To address these challenges, this paper proposes a robust delineation model based on a convolutional recurrent network with grid search optimization, aiming to classify the precise P-QRS-T waves. In order to make a delineation decision, the results from the ECG waveform classification model are utilized to interpret morphological abnormalities, based on medical knowledge. We generated 36 models, and the model with the best results achieved 99.97% accuracy, 99.92% sensitivity, and 99.93% precision for ECG waveform classification (P-wave, QRS-complex, T-wave, and isoelectric line class). To ensure the model robustness, we evaluated delineation model performance on seven different types of ECG datasets, namely the Lobachevsky University Electrocardiography Database (LUDB), QT Database (QTDB), the PhysioNet/Computing in Cardiology Challenge 2017, China Physiological Signal Challenge 2018, ECG Arrhythmia of Chapman University, MIT-BIH Arrhythmia Database and General Mohammad Hossein Hospital (Indonesia) databases. To detect the patterns of ECG morphological abnormalities through proposed delineation model, we focus on investigating arrhythmias. This process is based on two inputs examination: the P-wave and the regular/irregular rhythm of the RR interval. As the results, the proposed method has considerable capability to interpret the delineation result in cases with artifact noise, baseline drift and abnormal morphologies for delivering robust ECG delineation. Nature Publishing Group UK 2023-08-23 /pmc/articles/PMC10447439/ /pubmed/37612382 http://dx.doi.org/10.1038/s41598-023-40965-1 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Nurmaini, Siti
Darmawahyuni, Annisa
Rachmatullah, Muhammad Naufal
Firdaus, Firdaus
Sapitri, Ade Iriani
Tutuko, Bambang
Tondas, Alexander Edo
Putra, Muhammad Hafizh Permana
Islami, Anggun
Robust electrocardiogram delineation model for automatic morphological abnormality interpretation
title Robust electrocardiogram delineation model for automatic morphological abnormality interpretation
title_full Robust electrocardiogram delineation model for automatic morphological abnormality interpretation
title_fullStr Robust electrocardiogram delineation model for automatic morphological abnormality interpretation
title_full_unstemmed Robust electrocardiogram delineation model for automatic morphological abnormality interpretation
title_short Robust electrocardiogram delineation model for automatic morphological abnormality interpretation
title_sort robust electrocardiogram delineation model for automatic morphological abnormality interpretation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447439/
https://www.ncbi.nlm.nih.gov/pubmed/37612382
http://dx.doi.org/10.1038/s41598-023-40965-1
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