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Single cell transcriptomic analyses implicate an immunosuppressive tumor microenvironment in pancreatic cancer liver metastasis
Pancreatic ductal adenocarcinoma (PDAC) is a highly metastatic disease refractory to all targeted and immune therapies. However, our understanding of PDAC microenvironment especially the metastatic microenvironment is very limited partly due to the inaccessibility to metastatic tumor tissues. Here,...
Autores principales: | Zhang, Shu, Fang, Wen, Zhou, Siqi, Zhu, Dongming, Chen, Ruidong, Gao, Xin, Li, Zhuojin, Fu, Yao, Zhang, Yixuan, Yang, Fa, Zhao, Jing, Wu, Hao, Wang, Pin, Shen, Yonghua, Shen, Shanshan, Xu, Guifang, Wang, Lei, Yan, Chao, Zou, Xiaoping, Chen, Dijun, Lv, Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447466/ https://www.ncbi.nlm.nih.gov/pubmed/37612267 http://dx.doi.org/10.1038/s41467-023-40727-7 |
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