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Higher versus lower nut consumption and changes in cognitive performance over two years in a population at risk of cognitive decline: a cohort study
BACKGROUND: Tree nuts and peanuts (henceforth, nuts) are nutrient-dense foods rich in neuroprotective components; thus, their consumption could benefit cognitive health. However, evidence to date is limited and inconsistent regarding the potential benefits of nuts for cognitive function. OBJECTIVE:...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Nutrition
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447472/ https://www.ncbi.nlm.nih.gov/pubmed/37269908 http://dx.doi.org/10.1016/j.ajcnut.2023.05.032 |
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author | Ni, Jiaqi Nishi, Stephanie K. Babio, Nancy Ros, Emilio Basterra-Gortari, F Javier Corella, Dolores O, Castañer Martínez, J Alfredo Alonso-Gómez, Ángel M. Wärnberg, Julia Vioque, Jesús Romaguera, Dora López-Miranda, José Estruch, Ramon Tinahones, Francisco J. Santos-Lozano, José Manuel Serra-Majem, Lluís Cano-Ibáñez, Naomi Tur, Josep A. Fernández-García, José Manuel Pintó, Xavier Delgado-Rodríguez, Miguel Matía-Martín, Pilar Vidal, Josep Vázquez, Clotilde Daimiel, Lidia Fernández-Aranda, Fernando Ruiz-Canela, Miguel Mestres Solà, Cristina Portolés, Olga Sala-Vila, Aleix Garcia-Rios, Antonio Compañ-Gabucio, Laura María Gómez-Gracia, Enrique Zulet, M Angeles Chaplin, Alice Casas, Rosa Martínez-Diz, Silvia Tojal-Sierra, Lucas Gómez-Pérez, Ana María Toledo, Estefanía Rios, Santiago Ortega-Azorín, Carolina de la Torre, Rafael Peña-Orihuela, Patricia J. Garcia-de la Hera, Manuela Sayón-Orea, Carmen Malcampo, Mireia Salas-Salvadó, Jordi |
author_facet | Ni, Jiaqi Nishi, Stephanie K. Babio, Nancy Ros, Emilio Basterra-Gortari, F Javier Corella, Dolores O, Castañer Martínez, J Alfredo Alonso-Gómez, Ángel M. Wärnberg, Julia Vioque, Jesús Romaguera, Dora López-Miranda, José Estruch, Ramon Tinahones, Francisco J. Santos-Lozano, José Manuel Serra-Majem, Lluís Cano-Ibáñez, Naomi Tur, Josep A. Fernández-García, José Manuel Pintó, Xavier Delgado-Rodríguez, Miguel Matía-Martín, Pilar Vidal, Josep Vázquez, Clotilde Daimiel, Lidia Fernández-Aranda, Fernando Ruiz-Canela, Miguel Mestres Solà, Cristina Portolés, Olga Sala-Vila, Aleix Garcia-Rios, Antonio Compañ-Gabucio, Laura María Gómez-Gracia, Enrique Zulet, M Angeles Chaplin, Alice Casas, Rosa Martínez-Diz, Silvia Tojal-Sierra, Lucas Gómez-Pérez, Ana María Toledo, Estefanía Rios, Santiago Ortega-Azorín, Carolina de la Torre, Rafael Peña-Orihuela, Patricia J. Garcia-de la Hera, Manuela Sayón-Orea, Carmen Malcampo, Mireia Salas-Salvadó, Jordi |
author_sort | Ni, Jiaqi |
collection | PubMed |
description | BACKGROUND: Tree nuts and peanuts (henceforth, nuts) are nutrient-dense foods rich in neuroprotective components; thus, their consumption could benefit cognitive health. However, evidence to date is limited and inconsistent regarding the potential benefits of nuts for cognitive function. OBJECTIVE: To prospectively evaluate the association between nut consumption and 2-y changes in cognitive performance in older adults at cognitive decline risk. METHODS: A total of 6,630 participants aged 55 to 75 y (mean age 65.0±4.9 y, 48.4% women) with overweight/obesity and metabolic syndrome completed a validated semi-quantitative food frequency questionnaire and a comprehensive battery of neuropsychological tests at baseline and a 2-y follow-up. Composite cognitive scores were used to assess global, general, attention, and executive function domains. Nut consumption was categorized as <1, ≥1 to <3, ≥3 to <7, and ≥7 servings/wk (1 serving=30 g). Multivariable-adjusted linear regression models were fitted to assess associations between baseline nut consumption and 2-y cognitive changes. RESULTS: Nut consumption was positively associated with 2-y changes in general cognitive function (P-trend <0.001). Compared with participants consuming <1 serving/wk of nuts, those categorized as consuming ≥3 to <7 and ≥7 servings/wk showed more favorable changes in general cognitive performance (β z-score [95% CI] = 0.06 [0.00,0.12] and 0.13 [0.06,0.20], respectively). No significant changes were observed in the multivariable-adjusted models for other cognitive domains assessed. CONCLUSION: Frequent nut consumption was associated with a smaller decline in general cognitive performance over 2 y in older adults at risk of cognitive decline. Randomized clinical trials to verify our findings are warranted. |
format | Online Article Text |
id | pubmed-10447472 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | American Society for Nutrition |
record_format | MEDLINE/PubMed |
spelling | pubmed-104474722023-08-25 Higher versus lower nut consumption and changes in cognitive performance over two years in a population at risk of cognitive decline: a cohort study Ni, Jiaqi Nishi, Stephanie K. Babio, Nancy Ros, Emilio Basterra-Gortari, F Javier Corella, Dolores O, Castañer Martínez, J Alfredo Alonso-Gómez, Ángel M. Wärnberg, Julia Vioque, Jesús Romaguera, Dora López-Miranda, José Estruch, Ramon Tinahones, Francisco J. Santos-Lozano, José Manuel Serra-Majem, Lluís Cano-Ibáñez, Naomi Tur, Josep A. Fernández-García, José Manuel Pintó, Xavier Delgado-Rodríguez, Miguel Matía-Martín, Pilar Vidal, Josep Vázquez, Clotilde Daimiel, Lidia Fernández-Aranda, Fernando Ruiz-Canela, Miguel Mestres Solà, Cristina Portolés, Olga Sala-Vila, Aleix Garcia-Rios, Antonio Compañ-Gabucio, Laura María Gómez-Gracia, Enrique Zulet, M Angeles Chaplin, Alice Casas, Rosa Martínez-Diz, Silvia Tojal-Sierra, Lucas Gómez-Pérez, Ana María Toledo, Estefanía Rios, Santiago Ortega-Azorín, Carolina de la Torre, Rafael Peña-Orihuela, Patricia J. Garcia-de la Hera, Manuela Sayón-Orea, Carmen Malcampo, Mireia Salas-Salvadó, Jordi Am J Clin Nutr Original Research Article BACKGROUND: Tree nuts and peanuts (henceforth, nuts) are nutrient-dense foods rich in neuroprotective components; thus, their consumption could benefit cognitive health. However, evidence to date is limited and inconsistent regarding the potential benefits of nuts for cognitive function. OBJECTIVE: To prospectively evaluate the association between nut consumption and 2-y changes in cognitive performance in older adults at cognitive decline risk. METHODS: A total of 6,630 participants aged 55 to 75 y (mean age 65.0±4.9 y, 48.4% women) with overweight/obesity and metabolic syndrome completed a validated semi-quantitative food frequency questionnaire and a comprehensive battery of neuropsychological tests at baseline and a 2-y follow-up. Composite cognitive scores were used to assess global, general, attention, and executive function domains. Nut consumption was categorized as <1, ≥1 to <3, ≥3 to <7, and ≥7 servings/wk (1 serving=30 g). Multivariable-adjusted linear regression models were fitted to assess associations between baseline nut consumption and 2-y cognitive changes. RESULTS: Nut consumption was positively associated with 2-y changes in general cognitive function (P-trend <0.001). Compared with participants consuming <1 serving/wk of nuts, those categorized as consuming ≥3 to <7 and ≥7 servings/wk showed more favorable changes in general cognitive performance (β z-score [95% CI] = 0.06 [0.00,0.12] and 0.13 [0.06,0.20], respectively). No significant changes were observed in the multivariable-adjusted models for other cognitive domains assessed. CONCLUSION: Frequent nut consumption was associated with a smaller decline in general cognitive performance over 2 y in older adults at risk of cognitive decline. Randomized clinical trials to verify our findings are warranted. American Society for Nutrition 2023-08 2023-06-01 /pmc/articles/PMC10447472/ /pubmed/37269908 http://dx.doi.org/10.1016/j.ajcnut.2023.05.032 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Research Article Ni, Jiaqi Nishi, Stephanie K. Babio, Nancy Ros, Emilio Basterra-Gortari, F Javier Corella, Dolores O, Castañer Martínez, J Alfredo Alonso-Gómez, Ángel M. Wärnberg, Julia Vioque, Jesús Romaguera, Dora López-Miranda, José Estruch, Ramon Tinahones, Francisco J. Santos-Lozano, José Manuel Serra-Majem, Lluís Cano-Ibáñez, Naomi Tur, Josep A. Fernández-García, José Manuel Pintó, Xavier Delgado-Rodríguez, Miguel Matía-Martín, Pilar Vidal, Josep Vázquez, Clotilde Daimiel, Lidia Fernández-Aranda, Fernando Ruiz-Canela, Miguel Mestres Solà, Cristina Portolés, Olga Sala-Vila, Aleix Garcia-Rios, Antonio Compañ-Gabucio, Laura María Gómez-Gracia, Enrique Zulet, M Angeles Chaplin, Alice Casas, Rosa Martínez-Diz, Silvia Tojal-Sierra, Lucas Gómez-Pérez, Ana María Toledo, Estefanía Rios, Santiago Ortega-Azorín, Carolina de la Torre, Rafael Peña-Orihuela, Patricia J. Garcia-de la Hera, Manuela Sayón-Orea, Carmen Malcampo, Mireia Salas-Salvadó, Jordi Higher versus lower nut consumption and changes in cognitive performance over two years in a population at risk of cognitive decline: a cohort study |
title | Higher versus lower nut consumption and changes in cognitive performance over two years in a population at risk of cognitive decline: a cohort study |
title_full | Higher versus lower nut consumption and changes in cognitive performance over two years in a population at risk of cognitive decline: a cohort study |
title_fullStr | Higher versus lower nut consumption and changes in cognitive performance over two years in a population at risk of cognitive decline: a cohort study |
title_full_unstemmed | Higher versus lower nut consumption and changes in cognitive performance over two years in a population at risk of cognitive decline: a cohort study |
title_short | Higher versus lower nut consumption and changes in cognitive performance over two years in a population at risk of cognitive decline: a cohort study |
title_sort | higher versus lower nut consumption and changes in cognitive performance over two years in a population at risk of cognitive decline: a cohort study |
topic | Original Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447472/ https://www.ncbi.nlm.nih.gov/pubmed/37269908 http://dx.doi.org/10.1016/j.ajcnut.2023.05.032 |
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