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Hematopoietic stem cell aging and leukemia transformation

With aging, hematopoietic stem cells (HSCs) have an impaired ability to regenerate, differentiate, and produce an entire repertoire of mature blood and immune cells. Owing to dysfunctional hematopoiesis, the incidence of hematologic malignancies increases among elderly individuals. Here, we provide...

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Detalles Bibliográficos
Autores principales:	Colom Díaz, Patricia A., Mistry, Jayna J., Trowbridge, Jennifer J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society of Hematology 2023
Materias:	Hematopoietic Stem Cells
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447482/ https://www.ncbi.nlm.nih.gov/pubmed/36800569 http://dx.doi.org/10.1182/blood.2022017933

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