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Targeting LGSN restores sensitivity to chemotherapy in gastric cancer stem cells by triggering pyroptosis

Gastric cancer (GC) is notoriously resistant to current therapies due to tumor heterogeneity. Cancer stem cells (CSCs) possess infinite self-renewal potential and contribute to the inherent heterogeneity of GC. Despite its crucial role in chemoresistance, the mechanism of stemness maintenance of gas...

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Detalles Bibliográficos
Autores principales:	Li, Yu-Ting, Tan, Xiang-Yu, Ma, Li-Xiang, Li, Hua-Hui, Zhang, Shu-Hong, Zeng, Chui-Mian, Huang, Liu-Na, Xiong, Ji-Xian, Fu, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447538/ https://www.ncbi.nlm.nih.gov/pubmed/37612301 http://dx.doi.org/10.1038/s41419-023-06081-8

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