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ACE2 overexpression in corticotropin-releasing-hormone cells offers protection against pulmonary hypertension

BACKGROUND: Pulmonary hypertension (PH), characterized by elevated pulmonary pressure and right heart failure, is a systemic disease involving inappropriate sympathetic activation and an impaired gut-brain-lung axis. Global overexpression of angiotensin converting enzyme 2 (ACE2), a cardiopulmonary...

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Detalles Bibliográficos
Autores principales: Oliveira, Aline C., Karas, Marianthi M., Alves, Matthew, He, Jacky, de Kloet, Annette D., Krause, Eric G., Richards, Elaine M., Bryant, Andrew J., Raizada, Mohan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447887/
https://www.ncbi.nlm.nih.gov/pubmed/37638323
http://dx.doi.org/10.3389/fnins.2023.1223733