A tetracationic porphyrin with dual anti-prion activity

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Prions are deadly infectious agents made of PrP(Sc), a misfolded variant of the cellular prion protein (PrP(C)) which self-propagates by inducing misfolding of native PrP(C). PrP(Sc) can adopt different pathogenic conformations (prion strains), which can be resistant to potential drugs, or acquire d...

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Detalles Bibliográficos
Autores principales: Masone, Antonio, Zucchelli, Chiara, Caruso, Enrico, Lavigna, Giada, Eraña, Hasier, Giachin, Gabriele, Tapella, Laura, Comerio, Liliana, Restelli, Elena, Raimondi, Ilaria, Elezgarai, Saioa R., De Leo, Federica, Quilici, Giacomo, Taiarol, Lorenzo, Oldrati, Marvin, Lorenzo, Nuria L., García-Martínez, Sandra, Cagnotto, Alfredo, Lucchetti, Jacopo, Gobbi, Marco, Vanni, Ilaria, Nonno, Romolo, Di Bari, Michele A., Tully, Mark D., Cecatiello, Valentina, Ciossani, Giuseppe, Pasqualato, Sebastiano, Van Anken, Eelco, Salmona, Mario, Castilla, Joaquín, Requena, Jesús R., Banfi, Stefano, Musco, Giovanna, Chiesa, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448035/
https://www.ncbi.nlm.nih.gov/pubmed/37636075
http://dx.doi.org/10.1016/j.isci.2023.107480
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