Crystal structures of main proteases of SARS-CoV-2 variants bound to a benzothiazole-based inhibitor: Crystal structures of M (pro) mutants bound to YH-53

Main protease (M (pro)) serves as an indispensable factor in the life cycle of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as well as its constantly emerging variants and is therefore considered an attractive target for antiviral drug development. Benzothiazole-based inhibitors targ...

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Detalles Bibliográficos
Autores principales: Luo, Jiqing, Wang, Weiwei, Jiang, Haihai, Li, Wenwen, Zeng, Pei, Wang, Jie, Zhou, Xuelan, Zou, Xiaofang, Chen, Shenghui, Wang, Qisheng, Zhang, Jin, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448042/
https://www.ncbi.nlm.nih.gov/pubmed/37357528
http://dx.doi.org/10.3724/abbs.2023053

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