Homocysteine accelerates hepatocyte autophagy by upregulating TFEB via DNMT3b-mediated DNA hypomethylation: TFEB accelerates autophagy of hepatocytes with Hcy treatment

Autophagy plays a critical role in the physiology and pathophysiology of hepatocytes. High level of homocysteine (Hcy) promotes autophagy in hepatocytes, but the underlying mechanism is still unknown. Here, we investigate the relationship between Hcy-induced autophagy level and the expression of nuc...

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Detalles Bibliográficos
Autores principales: Yang, Anning, Zeng, Wen, Zhang, Hongwen, Hao, Yinju, Wang, Qingqing, Sun, Yue, Quan, Shangkun, Ding, Ning, Yang, Xiaoling, Sun, Jianmin, Zhang, Huiping, Liu, Bin, Jiao, Yun, Wu, Kai, Jiang, Yideng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448047/
https://www.ncbi.nlm.nih.gov/pubmed/37021975
http://dx.doi.org/10.3724/abbs.2023060

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