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Perioperative Factors Associated With Chronic Opioid Use After Spine Surgery
STUDY DESIGN: Retrospective case control. OBJECTIVES: The purpose of the current study is to determine risk factors associated with chronic opioid use after spine surgery. METHODS: In our single institution retrospective study, 1,299 patients undergoing elective spine surgery at a tertiary academic...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448093/ https://www.ncbi.nlm.nih.gov/pubmed/34414800 http://dx.doi.org/10.1177/21925682211035723 |
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author | Montgomery, Eric Y. Pernik, Mark N. Johnson, Zachary D. Dosselman, Luke J. Christian, Zachary K. Deme, Palvasha R. Adeyemo, Emmanuel A. Barrie, Umaru Badejo, Olatunde Stewart, Nick A. Uttarkar, Ruta Adogwa, Owoicho Tecle, Najib El Aoun, Salah G. Bagley, Carlos A. |
author_facet | Montgomery, Eric Y. Pernik, Mark N. Johnson, Zachary D. Dosselman, Luke J. Christian, Zachary K. Deme, Palvasha R. Adeyemo, Emmanuel A. Barrie, Umaru Badejo, Olatunde Stewart, Nick A. Uttarkar, Ruta Adogwa, Owoicho Tecle, Najib El Aoun, Salah G. Bagley, Carlos A. |
author_sort | Montgomery, Eric Y. |
collection | PubMed |
description | STUDY DESIGN: Retrospective case control. OBJECTIVES: The purpose of the current study is to determine risk factors associated with chronic opioid use after spine surgery. METHODS: In our single institution retrospective study, 1,299 patients undergoing elective spine surgery at a tertiary academic medical center between January 2010 and August 2017 were enrolled into a prospectively collected registry. Patients were dichotomized based on renewal of, or active opioid prescription at 3-mo and 12-mo postoperatively. The primary outcome measures were risk factors for opioid renewal 3-months and 12-months postoperatively. These primarily included demographic characteristics, operative variables, and in-hospital opioid consumption via morphine milligram equivalence (MME). At the 3-month and 12-month periods, we analyzed the aforementioned covariates with multivariate followed by bivariate regression analyses. RESULTS: Multivariate and bivariate analyses revealed that script renewal at 3 months was associated with black race (P = 0.001), preoperative narcotic (P < 0.001) or anxiety/depression medication use (P = 0.002), and intraoperative long lumbar (P < 0.001) or thoracic spine surgery (P < 0.001). Lower patient income was also a risk factor for script renewal (P = 0.01). Script renewal at 12 months was associated with younger age (P = 0.006), preoperative narcotics use (P = 0.001), and ≥4 levels of lumbar fusion (P < 0.001). Renewals at 3-mo and 12-mo had no association with MME given during the hospital stay or with the usage of PCA (P > 0.05). CONCLUSION: The current study describes multiple patient-level factors associated with chronic opioid use. Notably, no metric of perioperative opioid utilization was directly associated with chronic opioid use after multivariate analysis. |
format | Online Article Text |
id | pubmed-10448093 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-104480932023-08-25 Perioperative Factors Associated With Chronic Opioid Use After Spine Surgery Montgomery, Eric Y. Pernik, Mark N. Johnson, Zachary D. Dosselman, Luke J. Christian, Zachary K. Deme, Palvasha R. Adeyemo, Emmanuel A. Barrie, Umaru Badejo, Olatunde Stewart, Nick A. Uttarkar, Ruta Adogwa, Owoicho Tecle, Najib El Aoun, Salah G. Bagley, Carlos A. Global Spine J Original Articles STUDY DESIGN: Retrospective case control. OBJECTIVES: The purpose of the current study is to determine risk factors associated with chronic opioid use after spine surgery. METHODS: In our single institution retrospective study, 1,299 patients undergoing elective spine surgery at a tertiary academic medical center between January 2010 and August 2017 were enrolled into a prospectively collected registry. Patients were dichotomized based on renewal of, or active opioid prescription at 3-mo and 12-mo postoperatively. The primary outcome measures were risk factors for opioid renewal 3-months and 12-months postoperatively. These primarily included demographic characteristics, operative variables, and in-hospital opioid consumption via morphine milligram equivalence (MME). At the 3-month and 12-month periods, we analyzed the aforementioned covariates with multivariate followed by bivariate regression analyses. RESULTS: Multivariate and bivariate analyses revealed that script renewal at 3 months was associated with black race (P = 0.001), preoperative narcotic (P < 0.001) or anxiety/depression medication use (P = 0.002), and intraoperative long lumbar (P < 0.001) or thoracic spine surgery (P < 0.001). Lower patient income was also a risk factor for script renewal (P = 0.01). Script renewal at 12 months was associated with younger age (P = 0.006), preoperative narcotics use (P = 0.001), and ≥4 levels of lumbar fusion (P < 0.001). Renewals at 3-mo and 12-mo had no association with MME given during the hospital stay or with the usage of PCA (P > 0.05). CONCLUSION: The current study describes multiple patient-level factors associated with chronic opioid use. Notably, no metric of perioperative opioid utilization was directly associated with chronic opioid use after multivariate analysis. SAGE Publications 2021-08-20 2023-07 /pmc/articles/PMC10448093/ /pubmed/34414800 http://dx.doi.org/10.1177/21925682211035723 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc-nd/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/) which permits non-commercial use, reproduction and distribution of the work as published without adaptation or alteration, without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Articles Montgomery, Eric Y. Pernik, Mark N. Johnson, Zachary D. Dosselman, Luke J. Christian, Zachary K. Deme, Palvasha R. Adeyemo, Emmanuel A. Barrie, Umaru Badejo, Olatunde Stewart, Nick A. Uttarkar, Ruta Adogwa, Owoicho Tecle, Najib El Aoun, Salah G. Bagley, Carlos A. Perioperative Factors Associated With Chronic Opioid Use After Spine Surgery |
title | Perioperative Factors Associated With Chronic Opioid Use After Spine Surgery |
title_full | Perioperative Factors Associated With Chronic Opioid Use After Spine Surgery |
title_fullStr | Perioperative Factors Associated With Chronic Opioid Use After Spine Surgery |
title_full_unstemmed | Perioperative Factors Associated With Chronic Opioid Use After Spine Surgery |
title_short | Perioperative Factors Associated With Chronic Opioid Use After Spine Surgery |
title_sort | perioperative factors associated with chronic opioid use after spine surgery |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448093/ https://www.ncbi.nlm.nih.gov/pubmed/34414800 http://dx.doi.org/10.1177/21925682211035723 |
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