ER stress increases expression of intracellular calcium channel RyR1 to modify Ca(2+) homeostasis in pancreatic beta cells

Pancreatic beta cells maintain glucose homeostasis by secreting pulses of insulin in response to a rise in plasma glucose. Pulsatile insulin secretion occurs as a result of glucose-induced oscillations in beta-cell cytosolic Ca(2+). The endoplasmic reticulum (ER) helps regulate beta-cell cytosolic C...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Irina X., Herrmann, Andrea, Leon, Juan, Jeyarajan, Sivakumar, Arunagiri, Anoop, Arvan, Peter, Gilon, Patrick, Satin, Leslie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448220/
https://www.ncbi.nlm.nih.gov/pubmed/37468098
http://dx.doi.org/10.1016/j.jbc.2023.105065

Ejemplares similares

Ejemplares similares