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Effect of RUNX1/FOXP3 axis on apoptosis of T and B lymphocytes and immunosuppression in sepsis

Lymphocyte apoptosis is a latent factor for immunosuppression in sepsis. Forkhead box protein P3 (FOXP3) can interact with RUNX family transcription factor 1 (RUNX1) in regulatory T cells. Our research was to probe whether RUNX1/FOXP3 axis affects immunosuppression in the process of sepsis by modula...

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Detalles Bibliográficos
Autores principales: Chao, Yangfa, Huang, Wenting, Xu, Zhiheng, Li, Ping, Gu, Shaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448307/
https://www.ncbi.nlm.nih.gov/pubmed/37636994
http://dx.doi.org/10.1515/med-2023-0728