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Deriving a continuum score for group 3 and 4 medulloblastoma tumor samples analyzed via RNA-sequencing or DNA methylation microarray

Here, we present a protocol for deriving a continuum score for group 3 and 4 medulloblastoma tumor samples analyzed via RNA-sequencing or DNA methylation microarray. We describe steps for utilizing NMF-defined group 3/group 4 metagenes to calculate a continuum score between 0 and 1 that can be proje...

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Detalles Bibliográficos
Autores principales:	Hacking, James P.R., Thompson, Dean, Schwalbe, Edward C., Clifford, Steven C., Williamson, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448413/ https://www.ncbi.nlm.nih.gov/pubmed/37573504 http://dx.doi.org/10.1016/j.xpro.2023.102509

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