Large-scale assessment of pros and cons of autopsy-derived or tumor-matched tissues as the norms for gene expression analysis in cancers

Normal tissues are essential for studying disease-specific differential gene expression. However, healthy human controls are typically available only in postmortal/autopsy settings. In cancer research, fragments of pathologically normal tissue adjacent to tumor site are frequently used as the contro...

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Detalles Bibliográficos
Autores principales: Sorokin, Maksim, Buzdin, Anton A., Guryanova, Anastasia, Efimov, Victor, Suntsova, Maria V., Zolotovskaia, Marianna A., Koroleva, Elena V., Sekacheva, Marina I., Tkachev, Victor S., Garazha, Andrew, Kremenchutckaya, Kristina, Drobyshev, Aleksey, Seryakov, Aleksander, Gudkov, Alexander, Alekseenko, Irina V., Rakitina, Olga, Kostina, Maria B., Vladimirova, Uliana, Moisseev, Aleksey, Bulgin, Dmitry, Radomskaya, Elena, Shestakov, Viktor, Baklaushev, Vladimir P., Prassolov, Vladimir, Shegay, Petr V., Li, Xinmin, Poddubskaya, Elena V., Gaifullin, Nurshat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448432/
https://www.ncbi.nlm.nih.gov/pubmed/37635765
http://dx.doi.org/10.1016/j.csbj.2023.07.040

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