Cargando…

The GLP-1 agonist, exendin-4, stimulates LH secretion in female sheep

Our previous studies showed that microinjection into the median eminence of the sheep of glucagon-like peptide- 1 (GLP-1) or its receptor agonist exendin-4 stimulates luteinising hormone (LH) secretion, but it is unknown whether the same effect may be obtained by systemic administration of the same....

Descripción completa

Detalles Bibliográficos
Autores principales:	Simpson, Elizabeth M, Clarke, Iain J, Scott, Christopher J, Stephen, Cyril P, Rao, Alexandra, Gunn, Allan J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bioscientifica Ltd 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448581/ https://www.ncbi.nlm.nih.gov/pubmed/37466202 http://dx.doi.org/10.1530/JOE-23-0105

Ejemplares similares

Developmental programming: gestational testosterone excess disrupts LH secretion in the female sheep fetus
por: Landers, Renata S. M., et al.
Publicado: (2020)

Synthesis, Optimization, and Biological Evaluation of Corrinated Conjugates of the GLP-1R Agonist Exendin-4
por: Tinsley, Ian C., et al.
Publicado: (2021)

Combination of Obesity and High-Fat Feeding Diminishes Sensitivity to GLP-1R Agonist Exendin-4
por: Duca, Frank A., et al.
Publicado: (2013)

Type 2 diabetes-induced neuronal pathology in the piriform cortex of the rat is reversed by the GLP-1 receptor agonist exendin-4
por: Lietzau, Grazyna, et al.
Publicado: (2016)

Exendin‐4, a GLP‐1 receptor agonist regulates retinal capillary tone and restores microvascular patency after ischaemia–reperfusion injury
por: Zhai, Ruyi, et al.
Publicado: (2020)

Sex-dependent divergence in the effects of GLP-1 agonist exendin-4 on alcohol reinforcement and reinstatement in C57BL/6J mice
por: Díaz-Megido, Claudia, et al.
Publicado: (2023)

AWRK6, a Novel GLP-1 Receptor Agonist, Attenuates Diabetes by Stimulating Insulin Secretion
por: Wang, Qiuyu, et al.
Publicado: (2018)

The GLP-1R Agonist Exendin-4 Attenuates Hyperglycemia-Induced Chemoresistance in Human Endometrial Cancer Cells Through ROS-Mediated Mitochondrial Pathway
por: Zhang, Yu, et al.
Publicado: (2021)

Brain Imaging of the GLP-1 Receptor in Obesity Using (68)Ga-NODAGA-Exendin-4 PET
por: Deden, Laura N., et al.
Publicado: (2021)

Limiting glucocorticoid secretion increases the anorexigenic property of Exendin-4
por: Lee, Shin J., et al.
Publicado: (2016)

Purification and bioactivity of exendin-4, a peptide analogue of GLP-1, expressed in Pichia pastoris
por: Zhou, Jin, et al.
Publicado: (2007)

Gut Peptide GLP-1 and Its Analogue, Exendin-4, Decrease Alcohol Intake and Reward
por: Shirazi, Rozita H., et al.
Publicado: (2013)

GLP-1 Receptor Agonist Exendin-4 Attenuates NR4A Orphan Nuclear Receptor NOR1 Expression in Vascular Smooth Muscle Cells
por: Takahashi, Hiroyuki, et al.
Publicado: (2019)

The GLP-1 receptor agonists exendin-4 and liraglutide alleviate oxidative stress and cognitive and micturition deficits induced by middle cerebral artery occlusion in diabetic mice
por: Li, Ping-Chia, et al.
Publicado: (2016)

GLP-1 Receptor Agonists Induce Growth Hormone Secretion in Healthy Volunteers
por: Heinla, Keiu, et al.
Publicado: (2023)

Regulation of progesterone during follicular development by FSH and LH in sheep
por: Ding, Ziqiang, et al.
Publicado: (2022)

The GLP-1 Receptor Agonist Exendin-4 and Diazepam Differentially Regulate GABA(A) Receptor-Mediated Tonic Currents in Rat Hippocampal CA3 Pyramidal Neurons
por: Korol, Sergiy V., et al.
Publicado: (2015)

Role of Renal Sympathetic Nerves in GLP‐1 (Glucagon‐Like Peptide‐1) Receptor Agonist Exendin‐4‐Mediated Diuresis and Natriuresis in Diet‐Induced Obese Rats
por: Liu, Xuefei, et al.
Publicado: (2021)

(18)F-Labelled exendin to image GLP-1 receptor-expressing tissues: from niche to blockbuster?
por: Boerman, Otto C., et al.
Publicado: (2011)

Effect of the GLP-1 Analog Exendin-4 and Oxaliplatin on Intrahepatic Cholangiocarcinoma Cell Line and Mouse Model
por: Chen, Ben-Dong, et al.
Publicado: (2013)

GLP-1/Exendin-4 induces β-cell proliferation via the epidermal growth factor receptor
por: Fusco, Joseph, et al.
Publicado: (2017)

Signaling Mechanism for Modulation by GLP-1 and Exendin-4 of GABA Receptors on Rat Retinal Ganglion Cells
por: Zhang, Tao, et al.
Publicado: (2022)

Brain Site-Specific Inhibitory Effects of the GLP-1 Analogue Exendin-4 on Alcohol Intake and Operant Responding for Palatable Food
por: Colvin, Kayla J., et al.
Publicado: (2020)

Fructose stimulates GLP-1 but not GIP secretion in mice, rats, and humans
por: Kuhre, Rune E., et al.
Publicado: (2014)

The Role of the Medial and Central Amygdala in Stress-Induced Suppression of Pulsatile LH Secretion in Female Rats
por: Lin, Yuanshao, et al.
Publicado: (2011)

Role of CORT Duration and Estradiol Dependence for Stress-level of CORT to Inhibit Pulsatile LH Secretion in Female Mice
por: Kreisman, Michael J, et al.
Publicado: (2021)

The “Ram Effect”: A “Non-Classical” Mechanism for Inducing LH Surges in Sheep
por: Fabre-Nys, Claude, et al.
Publicado: (2016)

Differential Stimulation of Insulin Secretion by GLP-1 and Kisspeptin-10
por: Schwetz, Tara A., et al.
Publicado: (2014)

SUN-257 Evidence that Urocortin 2 Contributes to the Suppressive Effect of Metabolic Stress on LH Secretion in Female Mice
por: McCosh, Richard B, et al.
Publicado: (2020)

GLP-1R Agonist Exendin-4 Protects Against Hemorrhagic Transformation Induced by rtPA After Ischemic Stroke via the Wnt/β-Catenin Signaling Pathway
por: Liu, Chengli, et al.
Publicado: (2022)

Activation of Norepinephrine Neurons in the NTS (A2 population) is Sufficient to Suppress Pulsatile LH Secretion in Female Mice
por: McCosh, Richard B, et al.
Publicado: (2021)

The Cardiovascular Effects of GLP-1 Receptor Agonists
por: Okerson, Theodore, et al.
Publicado: (2012)

Evaluation of an [(18)F]AlF-NOTA Analog of Exendin-4 for Imaging of GLP-1 Receptor in Insulinoma
por: Kiesewetter, Dale O., et al.
Publicado: (2012)

Constitutive and agonist stimulated ATP secretion in leukocytes
por: Campwala, Hinnah, et al.
Publicado: (2013)

FRI279 Submaximal Loss Of KNDy Neurons Accelerates And Amplifies Pulsatile LH Secretion In Female Rats
por: Campideli-Santana, Ana C, et al.
Publicado: (2023)

Evaluation of efficacy- versus affinity-driven agonism with biased GLP-1R ligands P5 and exendin-F1
por: Marzook, Amaara, et al.
Publicado: (2021)

GLP-1 receptor agonists (GLP-1RAs): cardiovascular actions and therapeutic potential
por: Ma, Xiaoxuan, et al.
Publicado: (2021)

Conjugation to a cell-penetrating peptide drives the tumour accumulation of the GLP1R antagonist exendin(9-39)
por: Collado Camps, Estel, et al.
Publicado: (2022)

Future Perspectives on GLP-1 Receptor Agonists and GLP-1/glucagon Receptor Co-agonists in the Treatment of NAFLD
por: Seghieri, Marta, et al.
Publicado: (2018)

Novel GLP-1 Fusion Chimera as Potent Long Acting GLP-1 Receptor Agonist
por: Wang, Qinghua, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_crrajl4ahrvvicpfi0mmm2ena2