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Uncertainties in Markov State Models of Small Proteins

[Image: see text] Markov state models are widely used to describe and analyze protein dynamics based on molecular dynamics simulations, specifically to extract functionally relevant characteristic time scales and motions. Particularly for larger biomolecules such as proteins, however, insufficient s...

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Detalles Bibliográficos
Autores principales: Kozlowski, Nicolai, Grubmüller, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448719/
https://www.ncbi.nlm.nih.gov/pubmed/37540193
http://dx.doi.org/10.1021/acs.jctc.3c00372