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Perforated appendicitis treated with laparoscopic appendicectomy or open appendicectomy: A meta-analysis

AIM: This analysis compared the impact of laparoscopic appendicectomy (LA) and open appendicectomy (OA) on treating adult perforated appendicitis (PA). METHODS: Articles relating to LA and OA in treating PA were retrieved from databases including PubMed, Cochrane Library and Embase since their found...

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Autores principales: Gu, Qianquan, Hua, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449044/
https://www.ncbi.nlm.nih.gov/pubmed/37357489
http://dx.doi.org/10.4103/jmas.jmas_158_22
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author Gu, Qianquan
Hua, Ye
author_facet Gu, Qianquan
Hua, Ye
author_sort Gu, Qianquan
collection PubMed
description AIM: This analysis compared the impact of laparoscopic appendicectomy (LA) and open appendicectomy (OA) on treating adult perforated appendicitis (PA). METHODS: Articles relating to LA and OA in treating PA were retrieved from databases including PubMed, Cochrane Library and Embase since their founding to January 2022. These articles were independently filtered based on the inclusion and exclusion criteria by two investigators. The quality of these articles was assessed and article data were extracted. Dichotomous data were presented in the form of odd’s ratio (OR), whereas continuous data were in the form of weighted mean difference (WMD). The included articles reported at least one of the following outcomes: intra-abdominal abscess (IAA), wound infection, operative time, hospital stay and complications. RESULTS: Three randomised control trials (198 LA cases vs. 205 OA cases) and 12 case − control trials (914 LA cases vs. 2192 OA cases) were included. This analysis revealed that although the IAA formation rate was similar in the LA and OA groups (OR: 1.28, 95% confidence interval [CI]: 0.87–1.88), the wound infection rate was lower in the LA group (OR: 0.38, 95% CI: 0.28–0.51). Furthermore, LA was associated with shorter hospital stay (WMD: −1.43 days, 95% CI: −2.33–−0.52) and fewer complications than OA (OR: 0.40, 95% CI: 0.28–0.57). CONCLUSION: LA has significant benefits in treating PA and is associated with better post-operative outcomes such as shorter hospital stay, lower incidence of wound infection and other complications. However, more studies with randomised and large-sample populations are still required to determine the clinical benefit of LA in treating PA.
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spelling pubmed-104490442023-08-25 Perforated appendicitis treated with laparoscopic appendicectomy or open appendicectomy: A meta-analysis Gu, Qianquan Hua, Ye J Minim Access Surg Review Article AIM: This analysis compared the impact of laparoscopic appendicectomy (LA) and open appendicectomy (OA) on treating adult perforated appendicitis (PA). METHODS: Articles relating to LA and OA in treating PA were retrieved from databases including PubMed, Cochrane Library and Embase since their founding to January 2022. These articles were independently filtered based on the inclusion and exclusion criteria by two investigators. The quality of these articles was assessed and article data were extracted. Dichotomous data were presented in the form of odd’s ratio (OR), whereas continuous data were in the form of weighted mean difference (WMD). The included articles reported at least one of the following outcomes: intra-abdominal abscess (IAA), wound infection, operative time, hospital stay and complications. RESULTS: Three randomised control trials (198 LA cases vs. 205 OA cases) and 12 case − control trials (914 LA cases vs. 2192 OA cases) were included. This analysis revealed that although the IAA formation rate was similar in the LA and OA groups (OR: 1.28, 95% confidence interval [CI]: 0.87–1.88), the wound infection rate was lower in the LA group (OR: 0.38, 95% CI: 0.28–0.51). Furthermore, LA was associated with shorter hospital stay (WMD: −1.43 days, 95% CI: −2.33–−0.52) and fewer complications than OA (OR: 0.40, 95% CI: 0.28–0.57). CONCLUSION: LA has significant benefits in treating PA and is associated with better post-operative outcomes such as shorter hospital stay, lower incidence of wound infection and other complications. However, more studies with randomised and large-sample populations are still required to determine the clinical benefit of LA in treating PA. Wolters Kluwer - Medknow 2023 2023-05-29 /pmc/articles/PMC10449044/ /pubmed/37357489 http://dx.doi.org/10.4103/jmas.jmas_158_22 Text en Copyright: © 2023 Journal of Minimal Access Surgery https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Review Article
Gu, Qianquan
Hua, Ye
Perforated appendicitis treated with laparoscopic appendicectomy or open appendicectomy: A meta-analysis
title Perforated appendicitis treated with laparoscopic appendicectomy or open appendicectomy: A meta-analysis
title_full Perforated appendicitis treated with laparoscopic appendicectomy or open appendicectomy: A meta-analysis
title_fullStr Perforated appendicitis treated with laparoscopic appendicectomy or open appendicectomy: A meta-analysis
title_full_unstemmed Perforated appendicitis treated with laparoscopic appendicectomy or open appendicectomy: A meta-analysis
title_short Perforated appendicitis treated with laparoscopic appendicectomy or open appendicectomy: A meta-analysis
title_sort perforated appendicitis treated with laparoscopic appendicectomy or open appendicectomy: a meta-analysis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449044/
https://www.ncbi.nlm.nih.gov/pubmed/37357489
http://dx.doi.org/10.4103/jmas.jmas_158_22
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