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Icenticaftor, a CFTR Potentiator, in COPD: A Multicenter, Parallel-Group, Double-Blind Clinical Trial

RATIONALE: CFTR (cystic fibrosis transmembrane conductance regulator) dysfunction is associated with mucus accumulation and worsening chronic obstructive pulmonary disease (COPD) symptoms. OBJECTIVES: The aim of this phase IIb dose-finding study was to compare a CFTR potentiator, icenticaftor (QBW25...

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Detalles Bibliográficos
Autores principales:	Martinez, Fernando J., Criner, Gerard J., Gessner, Christian, Jandl, Margret, Scherbovsky, Fernando, Shinkai, Masaharu, Siler, Thomas M., Vogelmeier, Claus F., Voves, Robert, Wedzicha, Jadwiga A., Bartels, Christian, Bottoli, Ivan, Byiers, Stuart, Cardenas, Pamela, Eckert, Joerg H., Gutzwiller, Florian S., Knorr, Barbara, Kothari, Mahavir, Parlikar, Rutvick, Tanase, Ana-Maria, Franssen, Frits M.E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Thoracic Society 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449083/ https://www.ncbi.nlm.nih.gov/pubmed/37411039 http://dx.doi.org/10.1164/rccm.202303-0458OC

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