Cargando…

Deconvolution of cancer cell states by the XDec-SM method

Proper characterization of cancer cell states within the tumor microenvironment is a key to accurately identifying matching experimental models and the development of precision therapies. To reconstruct this information from bulk RNA-seq profiles, we developed the XDec Simplex Mapping (XDec-SM) refe...

Descripción completa

Detalles Bibliográficos
Autores principales: Murillo, Oscar D., Petrosyan, Varduhi, LaPlante, Emily L., Dobrolecki, Lacey E., Lewis, Michael T., Milosavljevic, Aleksandar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449115/
https://www.ncbi.nlm.nih.gov/pubmed/37578979
http://dx.doi.org/10.1371/journal.pcbi.1011365