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Deconvolution of cancer cell states by the XDec-SM method
Proper characterization of cancer cell states within the tumor microenvironment is a key to accurately identifying matching experimental models and the development of precision therapies. To reconstruct this information from bulk RNA-seq profiles, we developed the XDec Simplex Mapping (XDec-SM) refe...
Autores principales: | Murillo, Oscar D., Petrosyan, Varduhi, LaPlante, Emily L., Dobrolecki, Lacey E., Lewis, Michael T., Milosavljevic, Aleksandar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449115/ https://www.ncbi.nlm.nih.gov/pubmed/37578979 http://dx.doi.org/10.1371/journal.pcbi.1011365 |
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