Cargando…
Hyperglycemia alters retinoic acid catabolism in embryos exposed to a maternal diabetic milieu
Pregestational diabetes is highly associated with increased risk of birth defects. We previously reported that the expression of Cyp26a1, the major catabolizing enzyme for controlling retinoic acid (RA) homeostasis, is significantly down-regulated in embryos of diabetic mice, thereby increasing the...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449132/ https://www.ncbi.nlm.nih.gov/pubmed/37616226 http://dx.doi.org/10.1371/journal.pone.0287253 |