Cargando…

Crystallographic structure determination and analysis of a potential short-chain dehydrogenase/reductase (SDR) from multi-drug resistant Acinetobacter baumannii

Bacterial antibiotic resistance remains an ever-increasing worldwide problem, requiring new approaches and enzyme targets. Acinetobacter baumannii is recognised as one of the most significant antibiotic-resistant bacteria, capable of carrying up to 45 different resistance genes, and new drug discove...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ghafoori, Seyed Mohammad, Abdollahpour, Soha, Shirmast, Paniz, Forwood, Jade K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449147/ https://www.ncbi.nlm.nih.gov/pubmed/37616198 http://dx.doi.org/10.1371/journal.pone.0289992

Ejemplares similares

Structure of a short-chain dehydrogenase/reductase (SDR) within a genomic island from a clinical strain of Acinetobacter baumannii
por: Shah, Bhumika S., et al.
Publicado: (2014)

Gene Structure Evolution of the Short-Chain Dehydrogenase/Reductase (SDR) Family
por: Gabrielli, Franco, et al.
Publicado: (2022)

Medium- and short-chain dehydrogenase/reductase gene and protein families: MDR and SDR gene and protein superfamilies
por: Jörnvall, H.
Publicado: (2008)

Genome-Wide Identification and Characterization of Short-Chain Dehydrogenase/Reductase (SDR) Gene Family in Medicago truncatula
por: Yu, Shuhan, et al.
Publicado: (2021)

Insights into Acinetobacter baumannii fatty acid synthesis 3-oxoacyl-ACP reductases
por: Cross, Emily M., et al.
Publicado: (2021)

The Plant Short-Chain Dehydrogenase (SDR) superfamily: genome-wide inventory and diversification patterns
por: Moummou, Hanane, et al.
Publicado: (2012)

Medium- and short-chain dehydrogenase/reductase gene and protein families: The SDR superfamily: functional and structural diversity within a family of metabolic and regulatory enzymes
por: Kavanagh, K. L., et al.
Publicado: (2008)

SDR7‐6, a short‐chain alcohol dehydrogenase/reductase family protein, regulates light‐dependent cell death and defence responses in rice
por: Zheng, Yanmei, et al.
Publicado: (2021)

Structural characterization of a Type B chloramphenicol acetyltransferase from the emerging pathogen Elizabethkingia anophelis NUHP1
por: Ghafoori, Seyed Mohammad, et al.
Publicado: (2021)

Enantiocomplementary Yarrowia lipolytica Oxidoreductases: Alcohol Dehydrogenase 2 and Short Chain Dehydrogenase/Reductase
por: Napora-Wijata, Kamila, et al.
Publicado: (2013)

Structural characterization of a GNAT family acetyltransferase from Elizabethkingia anophelis bound to acetyl-CoA reveals a new dimeric interface
por: Shirmast, P., et al.
Publicado: (2021)

Multiple short‐chain dehydrogenases/reductases are regulated in pathological cardiac hypertrophy
por: Roussel, Elise, et al.
Publicado: (2018)

The characterization of a short chain dehydrogenase/reductase (SDRx) in Comamonas testosteroni
por: Liu, Chuanzhi, et al.
Publicado: (2020)

Bioinformatic analysis of short-chain dehydrogenase/reductase proteins in plant peroxisomes
por: Zhang, Yuchan, et al.
Publicado: (2023)

Dehydrogenase reductase 9 (SDR9C4) and related homologs recognize a broad spectrum of lipid mediator oxylipins as substrates
por: Belyaeva, Olga V., et al.
Publicado: (2021)

Systematic Evaluation of Imine‐Reducing Enzymes: Common Principles in Imine Reductases, β‐Hydroxy Acid Dehydrogenases, and Short‐Chain Dehydrogenases/ Reductases
por: Stockinger, Peter, et al.
Publicado: (2020)

Medium- and short-chain dehydrogenase/reductase gene and protein families: The MDR superfamily
por: Persson, B., et al.
Publicado: (2008)

Crossing the Border: From Keto‐ to Imine Reduction in Short‐Chain Dehydrogenases/Reductases
por: Roth, Sebastian, et al.
Publicado: (2020)

Dimerization and enzymatic activity of fungal 17β-hydroxysteroid dehydrogenase from the short-chain dehydrogenase/reductase superfamily
por: Kristan, Katja, et al.
Publicado: (2005)

Delineating Substrate Diversity of Disparate Short-Chain Dehydrogenase Reductase from Debaryomyces hansenii
por: Ghatak, Arindam, et al.
Publicado: (2017)

Identification, Expression and Evolution of Short-Chain Dehydrogenases/Reductases in Nile Tilapia (Oreochromis niloticus)
por: Zhang, Shuai, et al.
Publicado: (2021)

Crystal structure of a putative short-chain dehydrogenase/reductase from Paraburkholderia xenovorans
por: Davidson, Jaysón, et al.
Publicado: (2022)

Repurposed dihydroorotate dehydrogenase inhibitors with efficacy against drug-resistant Acinetobacter baumannii
por: Russo, Thomas A., et al.
Publicado: (2022)

A role for the dehydrogenase DHRS7 (SDR34C1) in prostate cancer
por: Seibert, Julia K, et al.
Publicado: (2015)

Pinpointing a Mechanistic Switch Between Ketoreduction and “Ene” Reduction in Short‐Chain Dehydrogenases/Reductases
por: Lygidakis, Antonios, et al.
Publicado: (2016)

Pinpointing a Mechanistic Switch Between Ketoreduction and “Ene” Reduction in Short‐Chain Dehydrogenases/Reductases
por: Lygidakis, Antonios, et al.
Publicado: (2016)

Epimerisation of chiral hydroxylactones by short-chain dehydrogenases/reductases accounts for sex pheromone evolution in Nasonia
por: Ruther, Joachim, et al.
Publicado: (2016)

Crystal structure of a short-chain dehydrogenase/reductase from Burkholderia phymatum in complex with NAD
por: Alenazi, Jawaher, et al.
Publicado: (2022)

Structure-based identification of novel inhibitors targeting the enoyl-ACP reductase enzyme of Acinetobacter baumannii
por: Khan, Shama, et al.
Publicado: (2023)

Tackling Acinetobacter baumannii
por: Granata, Guido, et al.
Publicado: (2023)

Anti-Acinetobacter baumannii single-chain variable fragments show direct bactericidal activity
por: Basardeh, Eilnaz, et al.
Publicado: (2022)

Dehydrogenase/reductase SDR family member 2 silencing sensitizes an oxaliplatin-resistant cell line to oxaliplatin by inhibiting excision repair cross-complementing group 1 protein expression
por: Li, Ji-Min, et al.
Publicado: (2019)

Comparative Study on Sequence–Structure–Function Relationship of the Human Short-chain Dehydrogenases/Reductases Protein Family
por: Tang, Nu Thi Ngoc, et al.
Publicado: (2014)

Structure-guided design of Serratia marcescens short-chain dehydrogenase/reductase for stereoselective synthesis of (R)-phenylephrine
por: Liu, Jai-Shin, et al.
Publicado: (2018)

A poplar short-chain dehydrogenase reductase plays a potential key role in biphenyl detoxification
por: Contreras, Ángela, et al.
Publicado: (2021)

Role of Iron-Containing Alcohol Dehydrogenases in Acinetobacter baumannii ATCC 19606 Stress Resistance and Virulence
por: Lin, Guang-Huey, et al.
Publicado: (2021)

Biosynthesis of clinically used antibiotic fusidic acid and identification of two short-chain dehydrogenase/reductases with converse stereoselectivity
por: Cao, Zhiqin, et al.
Publicado: (2019)

Sortase A-mediated crosslinked short-chain dehydrogenases/reductases as novel biocatalysts with improved thermostability and catalytic efficiency
por: Li, Kunpeng, et al.
Publicado: (2017)

Tunable Toxicity of Bufadienolides is Regulated through a Configuration Inversion Catalyzed by a Short‐Chain Dehydrogenase/Reductase
por: Ye, Ge, et al.
Publicado: (2022)

SDR, EVC, and SDREVC: Limitations and Extensions
por: Hunter, E.D., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_6nvr71la2mp7rhj8hv7piuqrct