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Viral burden is associated with age, vaccination, and viral variant in a population-representative study of SARS-CoV-2 that accounts for time-since-infection-related sampling bias

In this study, we evaluated the impact of viral variant, in addition to other variables, on within-host viral burden, by analysing cycle threshold (Ct) values derived from nose and throat swabs, collected as part of the UK COVID-19 Infection Survey. Because viral burden distributions determined from...

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Detalles Bibliográficos
Autores principales: Fryer, Helen R., Golubchik, Tanya, Hall, Matthew, Fraser, Christophe, Hinch, Robert, Ferretti, Luca, Thomson, Laura, Nurtay, Anel, Pellis, Lorenzo, House, Thomas, MacIntyre-Cockett, George, Trebes, Amy, Buck, David, Piazza, Paolo, Green, Angie, Lonie, Lorne J, Smith, Darren, Bashton, Matthew, Crown, Matthew, Nelson, Andrew, McCann, Clare M., Adnan Tariq, Mohammed, Elstob, Claire J., Nunes Dos Santos, Rui, Richards, Zack, Xhang, Xin, Hawley, Joseph, Lee, Mark R., Carrillo-Barragan, Priscilla, Chapman, Isobel, Harthern-Flint, Sarah, Bonsall, David, Lythgoe, Katrina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449197/
https://www.ncbi.nlm.nih.gov/pubmed/37578971
http://dx.doi.org/10.1371/journal.ppat.1011461