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Lobeglitazone inhibits LPS-induced NLRP3 inflammasome activation and inflammation in the liver
Liver inflammation is a common feature of chronic liver disease and is often associated with increased exposure of the liver to lipopolysaccharide (LPS). Kupffer cells (KCs) are macrophages in the liver and produce various cytokines. Activation of KCs through the NLRP3 inflammasome pathway leads to...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449201/ https://www.ncbi.nlm.nih.gov/pubmed/37616215 http://dx.doi.org/10.1371/journal.pone.0290532 |