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Lobeglitazone inhibits LPS-induced NLRP3 inflammasome activation and inflammation in the liver

Liver inflammation is a common feature of chronic liver disease and is often associated with increased exposure of the liver to lipopolysaccharide (LPS). Kupffer cells (KCs) are macrophages in the liver and produce various cytokines. Activation of KCs through the NLRP3 inflammasome pathway leads to...

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Detalles Bibliográficos
Autores principales: Seo, Hye-Young, Lee, So-Hee, Park, Ji Yeon, Han, Eugene, Han, Sol, Hwang, Jae Seok, Kim, Mi Kyung, Jang, Byoung Kuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449201/
https://www.ncbi.nlm.nih.gov/pubmed/37616215
http://dx.doi.org/10.1371/journal.pone.0290532