Case Report: Molecular and microenvironment change upon midostaurin treatment in mast cell leukemia at single-cell level

Mast cell leukemia is a rare and aggressive disease, predominantly with KIT D816V mutation. With poor response to conventional poly-chemotherapy, mast cell leukemia responded to the midostaurin treatment with a 50% overall response rate (ORR), but complete remission rate is approximately 0%. Therefo...

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Detalles Bibliográficos
Autores principales: Liu, Meng-Ke, Liu, Feng, Dai, Yu-Ting, Weng, Xiang-Qin, Cheng, Li-Li, Fan, Li-Quan, Liu, Han, Jiang, Lu, Sun, Xiao-Jian, Fang, Hai, Wang, Li, Zhao, Wei-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449247/
https://www.ncbi.nlm.nih.gov/pubmed/37638009
http://dx.doi.org/10.3389/fimmu.2023.1210909

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