Single-cell RNA-seq analysis reveals that immune cells induce human nucleus pulposus ossification and degeneration

BACKGROUND AND AIMS: Determining the transcriptomes and molecular mechanism underlying human degenerative nucleus pulposus (NP) is of critical importance for treating intervertebral disc degeneration (IDD). Here, we aimed to elucidate the detailed molecular mechanism of NP ossification and IDD using...

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Detalles Bibliográficos
Autores principales: Guo, Song, Yan, Meijun, Li, Xinhua, Zhang, Shuya, Liu, Zhong, Li, Kewei, Liu, Pengcheng, Liu, Yanbin, Sun, Guixin, Fu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449260/
https://www.ncbi.nlm.nih.gov/pubmed/37638033
http://dx.doi.org/10.3389/fimmu.2023.1224627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449260/
https://www.ncbi.nlm.nih.gov/pubmed/37638033
http://dx.doi.org/10.3389/fimmu.2023.1224627

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