Cargando…

MGME1 associates with poor prognosis and is vital for cell proliferation in lower-grade glioma

Objective: Mitochondrial genome maintenance exonuclease 1 (MGME1) is associated with DNA depletion, deletion, duplication, and rearrangement. However, the function of MGME1 in tumors, especially lower-grade gliomas (LGGs), has not been established. Methods: Pan-cancer analysis was used to define the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiao, Feng, Zeng, Jie, Wang, Haiyan, Zhu, Hong, Guo, Yun, Zhang, Zhe, Xiao, Yao, Hu, Guowen, Huang, Kai, Yang, Qing, Guo, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449294/ https://www.ncbi.nlm.nih.gov/pubmed/37166417 http://dx.doi.org/10.18632/aging.204705

Ejemplares similares

MAGOH is correlated with poor prognosis and is essential for cell proliferation in lower-grade glioma
por: Xiao, Feng, et al.
Publicado: (2023)

DUSP10 is a novel immune-related biomarker connected with survival and cellular proliferation in lower-grade glioma
por: Xiao, Feng, et al.
Publicado: (2023)

Hypomethylation of CNTFRα is associated with proliferation and poor prognosis in lower grade gliomas
por: Fan, Kun, et al.
Publicado: (2017)

PPP1R81 correlates with the survival and cell proliferation in lower-grade glioma
por: Xiao, Feng, et al.
Publicado: (2023)

Structural insights into DNA degradation by human mitochondrial nuclease MGME1
por: Yang, Chun, et al.
Publicado: (2018)

Deletion and low expression of NFKBIA are associated with poor prognosis in lower-grade glioma patients
por: Kinker, Gabriela Sarti, et al.
Publicado: (2016)

Identification of a Tumor Microenvironment-Related Eight-Gene Signature for Predicting Prognosis in Lower-Grade Gliomas
por: Su, Jun, et al.
Publicado: (2019)

DKK3 expression is associated with immunosuppression and poor prognosis in glioblastoma, in contrast to lower-grade gliomas
por: Han, Myung-Hoon, et al.
Publicado: (2023)

Mice lacking the mitochondrial exonuclease MGME1 develop inflammatory kidney disease with glomerular dysfunction
por: Milenkovic, Dusanka, et al.
Publicado: (2022)

Identification and Validation of a Seizure-Free-Related Gene Signature for Predicting Poor Prognosis in Lower-Grade Gliomas
por: Li, Jinxing, et al.
Publicado: (2021)

An Immune-Related Signature for Predicting the Prognosis of Lower-Grade Gliomas
por: Zhang, Hongbo, et al.
Publicado: (2020)

A Metabolic Plasticity-Based Signature for Molecular Classification and Prognosis of Lower-Grade Glioma
por: Yang, Ming-Chun, et al.
Publicado: (2022)

Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria
por: Matic, Stanka, et al.
Publicado: (2018)

Downregulation of LUZP2 Is Correlated with Poor Prognosis of Low-Grade Glioma
por: Li, Yong, et al.
Publicado: (2020)

Lower Grade Gliomas
por: Youssef, Gilbert, et al.
Publicado: (2020)

Low forced vital capacity predicts poor prognosis in gastric cancer patients
por: Feng, Fan, et al.
Publicado: (2017)

Low GAS5 Levels as a Predictor of Poor Survival in Patients with Lower-Grade Gliomas
por: Wang, Yanfang, et al.
Publicado: (2019)

Linear mtDNA fragments and unusual mtDNA rearrangements associated with pathological deficiency of MGME1 exonuclease
por: Nicholls, Thomas J., et al.
Publicado: (2014)

MGME1 processes flaps into ligatable nicks in concert with DNA polymerase γ during mtDNA replication
por: Uhler, Jay P., et al.
Publicado: (2016)

High Expression of PLAGL2 is Associated With Poor Prognosis in High-Grade Glioma
por: Wang, Gang, et al.
Publicado: (2022)

PDIA4 Correlates with Poor Prognosis and is a Potential Biomarker in Glioma
por: Li, Haoyu, et al.
Publicado: (2021)

The Higher Expression of CDCA2 Associated with Poor Prognosis in Glioma
por: Jin, Xin, et al.
Publicado: (2022)

Heterogeneity in clinical prognosis, immune infiltration and molecular characteristics of three glycolytic subtypes in lower-grade gliomas
por: Wu, Shenglian, et al.
Publicado: (2023)

Genomic instability in lower-grade glioma: Prediction of prognosis based on lncRNA and immune infiltration
por: Kang, Kai, et al.
Publicado: (2021)

The 5′-phosphate enhances the DNA-binding and exonuclease activities of human mitochondrial genome maintenance exonuclease 1 (MGME1)
por: Urrutia, Kathleen M., et al.
Publicado: (2022)

Immune Characteristics and Prognosis Analysis of the Proteasome 20S Subunit Beta 9 in Lower-Grade Gliomas
por: Liu, Junzhe, et al.
Publicado: (2022)

Identification and Potential Mechanisms of a 7-MicroRNA Signature That Predicts Prognosis in Patients with Lower-Grade Glioma
por: Liu, Zhizheng, et al.
Publicado: (2021)

Development and Verification of Glutamatergic Synapse-Associated Prognosis Signature for Lower-Grade Gliomas
por: Ye, Liguo, et al.
Publicado: (2021)

Establishment and Validation of a Ferroptosis-Related lncRNA Signature for Prognosis Prediction in Lower-Grade Glioma
por: Huang, Qian-Rong, et al.
Publicado: (2022)

A Novel Four-Gene Signature Associated With Immune Checkpoint for Predicting Prognosis in Lower-Grade Glioma
por: Xiao, Youchao, et al.
Publicado: (2020)

Overexpression of the phospholipase A2 group V gene in glioma tumors is associated with poor patient prognosis
por: Wu, Changwu, et al.
Publicado: (2019)

Decreased FOXD3 Expression Is Associated with Poor Prognosis in Patients with High-Grade Gliomas
por: Du, Wei, et al.
Publicado: (2015)

Elevated CD44 expression predicts poor prognosis in patients with low-grade glioma
por: Dong, Qiang, et al.
Publicado: (2019)

A Novel 10-Gene Signature Predicts Poor Prognosis in Low Grade Glioma
por: Liu, Wentao, et al.
Publicado: (2021)

Interfering with CALCRL expression inhibits glioma proliferation, promotes apoptosis, and predicts prognosis in low-grade gliomas
por: Gu, Shengcai, et al.
Publicado: (2022)

Identification and validation of a three-gene signature as a candidate prognostic biomarker for lower grade glioma
por: Xiao, Kai, et al.
Publicado: (2020)

Decreased SPTBN2 expression regulated by the ceRNA network is associated with poor prognosis and immune infiltration in low‑grade glioma
por: Chen, Guo-Rong, et al.
Publicado: (2023)

Dissection of transcriptomic and epigenetic heterogeneity of grade 4 gliomas: implications for prognosis
por: Zeng, Chang, et al.
Publicado: (2023)

Resilience in Lower Grade Glioma Patients
por: Fröhlich, Ellen, et al.
Publicado: (2022)

Preclinical modeling of lower-grade gliomas
por: Tang, Lilly W., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_vpn27aidib9a4i2prttk9vm4pk