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FAM46C-mediated tumor heterogeneity predicts extramedullary metastasis and poorer survival in multiple myeloma
Cancers originate from a single cell according to Nowell’s theory of clonal evolution. The enrichment of the most aggressive clones has been developed and the heterogeneity arises for genomic instability and environmental selection. Multiple myeloma (MM) is a multiple relapse plasma cell cancer gene...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449297/ https://www.ncbi.nlm.nih.gov/pubmed/37155154 http://dx.doi.org/10.18632/aging.204697 |