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Tumor-mediated immunosuppression and cytokine spreading affects the relation between EMT and PD-L1 status

Epithelial-mesenchymal transition (EMT) and immune resistance mediated by Programmed Death-Ligand 1 (PD-L1) upregulation are established drivers of tumor progression. Their bi-directional crosstalk has been proposed to facilitate tumor immunoevasion, yet the impact of immunosuppression and spatial h...

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Detalles Bibliográficos
Autores principales:	Lems, Carlijn M., Burger, Gerhard A., Beltman, Joost B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449452/ https://www.ncbi.nlm.nih.gov/pubmed/37638024 http://dx.doi.org/10.3389/fimmu.2023.1219669

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