Cargando…

Tumor-mediated immunosuppression and cytokine spreading affects the relation between EMT and PD-L1 status

Epithelial-mesenchymal transition (EMT) and immune resistance mediated by Programmed Death-Ligand 1 (PD-L1) upregulation are established drivers of tumor progression. Their bi-directional crosstalk has been proposed to facilitate tumor immunoevasion, yet the impact of immunosuppression and spatial h...

Descripción completa

Detalles Bibliográficos
Autores principales: Lems, Carlijn M., Burger, Gerhard A., Beltman, Joost B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449452/
https://www.ncbi.nlm.nih.gov/pubmed/37638024
http://dx.doi.org/10.3389/fimmu.2023.1219669

Ejemplares similares