Druggable redox pathways against Mycobacterium abscessus in cystic fibrosis patient-derived airway organoids

Mycobacterium abscessus (Mabs) drives life-shortening mortality in cystic fibrosis (CF) patients, primarily because of its resistance to chemotherapeutic agents. To date, our knowledge on the host and bacterial determinants driving Mabs pathology in CF patient lung remains rudimentary. Here, we used...

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Detalles Bibliográficos
Autores principales: Leon-Icaza, Stephen Adonai, Bagayoko, Salimata, Vergé, Romain, Iakobachvili, Nino, Ferrand, Chloé, Aydogan, Talip, Bernard, Célia, Sanchez Dafun, Angelique, Murris-Espin, Marlène, Mazières, Julien, Bordignon, Pierre Jean, Mazères, Serge, Bernes-Lasserre, Pascale, Ramé, Victoria, Lagarde, Jean-Michel, Marcoux, Julien, Bousquet, Marie-Pierre, Chalut, Christian, Guilhot, Christophe, Clevers, Hans, Peters, Peter J., Molle, Virginie, Lugo-Villarino, Geanncarlo, Cam, Kaymeuang, Berry, Laurence, Meunier, Etienne, Cougoule, Céline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449475/
https://www.ncbi.nlm.nih.gov/pubmed/37619220
http://dx.doi.org/10.1371/journal.ppat.1011559

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