CLK2 in GABAergic neurons is critical in regulating energy balance and anxiety-like behavior in a gender-specific fashion

INTRODUCTION: Cdc2-like kinase (CLK2) is a member of CLK kinases expressed in hypothalamic neurons and is activated in response to refeeding, leptin, or insulin. Diet-induced obesity and leptin receptor-deficient db/db mice lack CLK2 signal in the hypothalamic neurons. The neurotransmiter gamma-amin...

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Detalles Bibliográficos
Autores principales: Norberto, Sónia, Assalin, Heloisa Balan, Guadagnini, Dioze, Tobar, Natália, Boer, Patrícia Aline, Kang, Min-Cheol, Saad, Mario Jose Abdalla, Kim, Young-Bum, Prada, Patricia Oliveira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449579/
https://www.ncbi.nlm.nih.gov/pubmed/37635967
http://dx.doi.org/10.3389/fendo.2023.1172835

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