Structural basis for translation inhibition by the glycosylated drosocin peptide

The proline-rich antimicrobial peptide (PrAMP) drosocin is produced by Drosophila species to combat bacterial infection. Unlike many PrAMPs, drosocin is O-glycosylated at threonine 11, a post-translation modification that enhances its antimicrobial activity. Here we demonstrate that the O-glycosylat...

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Detalles Bibliográficos
Autores principales: Koller, Timm O., Morici, Martino, Berger, Max, Safdari, Haaris A., Lele, Deepti S., Beckert, Bertrand, Kaur, Kanwal J., Wilson, Daniel N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449632/
https://www.ncbi.nlm.nih.gov/pubmed/36997646
http://dx.doi.org/10.1038/s41589-023-01293-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449632/
https://www.ncbi.nlm.nih.gov/pubmed/36997646
http://dx.doi.org/10.1038/s41589-023-01293-7

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