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Structural basis for translation inhibition by the glycosylated drosocin peptide
The proline-rich antimicrobial peptide (PrAMP) drosocin is produced by Drosophila species to combat bacterial infection. Unlike many PrAMPs, drosocin is O-glycosylated at threonine 11, a post-translation modification that enhances its antimicrobial activity. Here we demonstrate that the O-glycosylat...
Autores principales: | Koller, Timm O., Morici, Martino, Berger, Max, Safdari, Haaris A., Lele, Deepti S., Beckert, Bertrand, Kaur, Kanwal J., Wilson, Daniel N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449632/ https://www.ncbi.nlm.nih.gov/pubmed/36997646 http://dx.doi.org/10.1038/s41589-023-01293-7 |
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