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Synergistic antitumor effects of circularly permuted TRAIL with doxorubicin in triple-negative breast cancer: Circularly permuted TRAIL with Dox in TNBC

Circularly permuted TRAIL (CPT), a novel recombinant TRAIL mutant, is a potent antitumor agent. However, its efficacy in triple-negative breast cancer (TNBC) remains unclear. Treatment with CPT alone and in combination with doxorubicin (Dox) is explored for its effects on the proliferation and apopt...

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Detalles Bibliográficos
Autores principales: Liu, Jia, Zhu, Tienian, Liu, Jiankun, Cui, Yujie, Yang, Shifang, Zhao, Ruijing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449636/
https://www.ncbi.nlm.nih.gov/pubmed/37559457
http://dx.doi.org/10.3724/abbs.2023160