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Radiation Dose and Fluoroscopy Time of Extracranial Carotid Artery Stenting: Elective vs. Emergency Treatment Including Combined Mechanical Thrombectomy in Tandem Occlusion

PURPOSE: Fluoroscopically guided endovascular carotid artery stenting (CAS) of extracranial carotid stenosis (ECS) is a reasonable alternative to carotid endarterectomy in selected patients. Diagnostic reference levels (DRL) for this common neurointervention have not yet been defined and respective...

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Autores principales: Forbrig, Robert, Ozpeynirci, Yigit, Fischer, Thomas David, Trumm, Christoph G., Liebig, Thomas, Stahl, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449680/
https://www.ncbi.nlm.nih.gov/pubmed/37261451
http://dx.doi.org/10.1007/s00062-023-01288-w
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author Forbrig, Robert
Ozpeynirci, Yigit
Fischer, Thomas David
Trumm, Christoph G.
Liebig, Thomas
Stahl, Robert
author_facet Forbrig, Robert
Ozpeynirci, Yigit
Fischer, Thomas David
Trumm, Christoph G.
Liebig, Thomas
Stahl, Robert
author_sort Forbrig, Robert
collection PubMed
description PURPOSE: Fluoroscopically guided endovascular carotid artery stenting (CAS) of extracranial carotid stenosis (ECS) is a reasonable alternative to carotid endarterectomy in selected patients. Diagnostic reference levels (DRL) for this common neurointervention have not yet been defined and respective literature data are sparse. We provide detailed dosimetrics for useful expansion of the DRL catalogue. METHODS: A retrospective single-center study of patients undergoing CAS between 2013 and 2021. We analyzed dose area product (DAP) and fluoroscopy time considering the following parameters: indications for CAS, semielective/elective versus emergency including additional mechanical thrombectomy (MT) in extracranial/intracranial tandem occlusion, etiology of ECS (atherosclerotic vs. radiation-induced), periprocedural features, e.g., number of applied stents, percutaneous transluminal angioplasty (PTA) and MT maneuvers, and dose protocol. Local DRL was defined as 75% percentile of the DAP distribution. RESULTS: A total of 102 patients were included (semielective/elective CAS n = 75, emergency CAS n = 8, CAS + MT n = 19). Total median DAP was 78.2 Gy cm(2) (DRL 117 Gy cm(2)). Lowest and highest median dosimetry values were documented for semielective/elective CAS and CAS + MT (DAP 49.1 vs. 146.8 Gy cm(2), fluoroscopy time 27.1 vs. 43.8 min; p < 0.005), respectively. Dosimetrics were significantly lower in patients undergoing 0–1 PTA maneuvers compared to ≥ 2 maneuvers (p < 0.05). Etiology of ECS, number of stents and MT maneuvers had no significant impact on dosimetry values (p > 0.05). A low-dose protocol yielded a 33% reduction of DAP. CONCLUSION: This CAS study suggests novel local DRLs for both elective and emergency cases with or without intracranial MT. A dedicated low-dose protocol was suitable for substantial reduction of radiation dose.
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spelling pubmed-104496802023-08-26 Radiation Dose and Fluoroscopy Time of Extracranial Carotid Artery Stenting: Elective vs. Emergency Treatment Including Combined Mechanical Thrombectomy in Tandem Occlusion Forbrig, Robert Ozpeynirci, Yigit Fischer, Thomas David Trumm, Christoph G. Liebig, Thomas Stahl, Robert Clin Neuroradiol Original Article PURPOSE: Fluoroscopically guided endovascular carotid artery stenting (CAS) of extracranial carotid stenosis (ECS) is a reasonable alternative to carotid endarterectomy in selected patients. Diagnostic reference levels (DRL) for this common neurointervention have not yet been defined and respective literature data are sparse. We provide detailed dosimetrics for useful expansion of the DRL catalogue. METHODS: A retrospective single-center study of patients undergoing CAS between 2013 and 2021. We analyzed dose area product (DAP) and fluoroscopy time considering the following parameters: indications for CAS, semielective/elective versus emergency including additional mechanical thrombectomy (MT) in extracranial/intracranial tandem occlusion, etiology of ECS (atherosclerotic vs. radiation-induced), periprocedural features, e.g., number of applied stents, percutaneous transluminal angioplasty (PTA) and MT maneuvers, and dose protocol. Local DRL was defined as 75% percentile of the DAP distribution. RESULTS: A total of 102 patients were included (semielective/elective CAS n = 75, emergency CAS n = 8, CAS + MT n = 19). Total median DAP was 78.2 Gy cm(2) (DRL 117 Gy cm(2)). Lowest and highest median dosimetry values were documented for semielective/elective CAS and CAS + MT (DAP 49.1 vs. 146.8 Gy cm(2), fluoroscopy time 27.1 vs. 43.8 min; p < 0.005), respectively. Dosimetrics were significantly lower in patients undergoing 0–1 PTA maneuvers compared to ≥ 2 maneuvers (p < 0.05). Etiology of ECS, number of stents and MT maneuvers had no significant impact on dosimetry values (p > 0.05). A low-dose protocol yielded a 33% reduction of DAP. CONCLUSION: This CAS study suggests novel local DRLs for both elective and emergency cases with or without intracranial MT. A dedicated low-dose protocol was suitable for substantial reduction of radiation dose. Springer Berlin Heidelberg 2023-06-01 2023 /pmc/articles/PMC10449680/ /pubmed/37261451 http://dx.doi.org/10.1007/s00062-023-01288-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Forbrig, Robert
Ozpeynirci, Yigit
Fischer, Thomas David
Trumm, Christoph G.
Liebig, Thomas
Stahl, Robert
Radiation Dose and Fluoroscopy Time of Extracranial Carotid Artery Stenting: Elective vs. Emergency Treatment Including Combined Mechanical Thrombectomy in Tandem Occlusion
title Radiation Dose and Fluoroscopy Time of Extracranial Carotid Artery Stenting: Elective vs. Emergency Treatment Including Combined Mechanical Thrombectomy in Tandem Occlusion
title_full Radiation Dose and Fluoroscopy Time of Extracranial Carotid Artery Stenting: Elective vs. Emergency Treatment Including Combined Mechanical Thrombectomy in Tandem Occlusion
title_fullStr Radiation Dose and Fluoroscopy Time of Extracranial Carotid Artery Stenting: Elective vs. Emergency Treatment Including Combined Mechanical Thrombectomy in Tandem Occlusion
title_full_unstemmed Radiation Dose and Fluoroscopy Time of Extracranial Carotid Artery Stenting: Elective vs. Emergency Treatment Including Combined Mechanical Thrombectomy in Tandem Occlusion
title_short Radiation Dose and Fluoroscopy Time of Extracranial Carotid Artery Stenting: Elective vs. Emergency Treatment Including Combined Mechanical Thrombectomy in Tandem Occlusion
title_sort radiation dose and fluoroscopy time of extracranial carotid artery stenting: elective vs. emergency treatment including combined mechanical thrombectomy in tandem occlusion
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449680/
https://www.ncbi.nlm.nih.gov/pubmed/37261451
http://dx.doi.org/10.1007/s00062-023-01288-w
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