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Large yellow croaker (Larimichthys crocea) mitofusin 2 inhibits type I IFN responses by degrading MAVS via enhanced K48-linked ubiquitination

In mammals, mitofusin 2 (MFN2) is involved in mitochondrial fusion, and suppresses the virus-induced RIG-I-like receptor (RLR) signaling pathway. However, little is known about the function of MFN2 in non-mammalian species. In the present study, we cloned an MFN2 ortholog (LcMFN2) in large yellow cr...

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Detalles Bibliográficos
Autores principales:	Li, Wen-Xing, Wang, Xiao-Hong, Lin, Yi-Jun, Zhou, Yuan-Yuan, Li, Jun, Zhang, Xiang-Yang, Chen, Xin-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Nature Singapore 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449736/ https://www.ncbi.nlm.nih.gov/pubmed/37637256 http://dx.doi.org/10.1007/s42995-023-00189-8

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