Different solubilizing ability of cyclodextrin derivatives for cholesterol in Niemann–Pick disease type C treatment

BACKGROUND: Niemann–Pick disease type C (NPC) is a fatal neurodegenerative disorder caused by abnormal intracellular cholesterol trafficking. Cyclodextrins (CDs), the most promising therapeutic candidates for NPC, but with concerns about ototoxicity, are cyclic oligosaccharides with dual functions o...

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Detalles Bibliográficos
Autores principales: Yamada, Yusei, Fukaura‐Nishizawa, Madoka, Nishiyama, Asami, Ishii, Akira, Kawata, Tatsuya, Shirakawa, Aina, Tanaka, Mayuko, Kondo, Yuki, Takeo, Toru, Nakagata, Naomi, Miwa, Toru, Takeda, Hiroki, Orita, Yorihisa, Motoyama, Keiichi, Higashi, Taishi, Arima, Hidetoshi, Seki, Takahiro, Kurauchi, Yuki, Katsuki, Hiroshi, Higaki, Katsumi, Minami, Kentaro, Yoshikawa, Naoki, Ikeda, Ryuji, Matsuo, Muneaki, Irie, Tetsumi, Ishitsuka, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449817/
https://www.ncbi.nlm.nih.gov/pubmed/37620691
http://dx.doi.org/10.1002/ctm2.1350

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