Cargando…
Circadian clock regulator Bmal1 gates axon regeneration via Tet3 epigenetics in mouse sensory neurons
Axon regeneration of dorsal root ganglia (DRG) neurons after peripheral axotomy involves reconfiguration of gene regulatory circuits to establish regenerative gene programs. However, the underlying mechanisms remain unclear. Here, through an unbiased survey, we show that the binding motif of Bmal1,...
Autores principales: | Halawani, Dalia, Wang, Yiqun, Ramakrishnan, Aarthi, Estill, Molly, He, Xijing, Shen, Li, Friedel, Roland H., Zou, Hongyan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449865/ https://www.ncbi.nlm.nih.gov/pubmed/37620297 http://dx.doi.org/10.1038/s41467-023-40816-7 |
Ejemplares similares
-
Aryl hydrocarbon receptor restricts axon regeneration of DRG neurons in response to injury
por: Wang, Yiqun, et al.
Publicado: (2023) -
Macrophages facilitate peripheral nerve regeneration by organizing regeneration tracks through Plexin-B2
por: Li, Yuhuan, et al.
Publicado: (2022) -
Regulation of circadian clock transcriptional output by CLOCK:BMAL1
por: Trott, Alexandra J., et al.
Publicado: (2018) -
BMAL1 dephosphorylation determines the pace of the circadian clock
por: Schibler, Ueli
Publicado: (2021) -
Interaction of circadian clock proteins PER2 and CRY with BMAL1 and CLOCK
por: Langmesser, Sonja, et al.
Publicado: (2008)