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A synthetic cell-free 36-enzyme reaction system for vitamin B(12) production
Adenosylcobalamin (AdoCbl), a biologically active form of vitamin B(12) (coenzyme B(12)), is one of the most complex metal-containing natural compounds and an essential vitamin for animals. However, AdoCbl can only be de novo synthesized by prokaryotes, and its industrial manufacturing to date was l...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449867/ https://www.ncbi.nlm.nih.gov/pubmed/37620358 http://dx.doi.org/10.1038/s41467-023-40932-4 |