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A synthetic cell-free 36-enzyme reaction system for vitamin B(12) production

Adenosylcobalamin (AdoCbl), a biologically active form of vitamin B(12) (coenzyme B(12)), is one of the most complex metal-containing natural compounds and an essential vitamin for animals. However, AdoCbl can only be de novo synthesized by prokaryotes, and its industrial manufacturing to date was l...

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Detalles Bibliográficos
Autores principales: Kang, Qian, Fang, Huan, Xiang, Mengjie, Xiao, Kaixing, Jiang, Pingtao, You, Chun, Lee, Sang Yup, Zhang, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449867/
https://www.ncbi.nlm.nih.gov/pubmed/37620358
http://dx.doi.org/10.1038/s41467-023-40932-4