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Astroglial exosome HepaCAM signaling and ApoE antagonization coordinates early postnatal cortical pyramidal neuronal axon growth and dendritic spine formation
Developing astroglia play important roles in regulating synaptogenesis through secreted and contact signals. Whether they regulate postnatal axon growth is unknown. By selectively isolating exosomes using size-exclusion chromatography (SEC) and employing cell-type specific exosome reporter mice, our...
Autores principales: | Jin, Shijie, Chen, Xuan, Tian, Yang, Jarvis, Rachel, Promes, Vanessa, Yang, Yongjie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449881/ https://www.ncbi.nlm.nih.gov/pubmed/37620511 http://dx.doi.org/10.1038/s41467-023-40926-2 |
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