Nuclear localization of TET2 requires β-catenin activation and correlates with favourable prognosis in colorectal cancer

Mutation-induced malfunction of ten-eleven translocation methylcytosine dioxygenase 2 (TET2) is widely reported in haematological malignancies. However, the role of TET2 in solid cancers, including colorectal cancer (CRC), is unclear. Here, we found that TET2 malfunction in CRC is mostly due to decr...

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Detalles Bibliográficos
Autores principales: Li, Changpeng, He, Jingcai, Meng, Fei, Wang, Fuhui, Sun, Hao, Zhang, Huizhong, Dong, Linna, Zhang, Mengdan, Xu, Qiaoran, Liang, Lining, Li, Yuan, Yang, Tingting, He, Meiai, Wang, Tao, Lin, Jiechun, Sun, Jiaqi, Huang, Qiuling, Guo, Lin, Zhang, Xiaofei, Mai, Shijuan, Zheng, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449923/
https://www.ncbi.nlm.nih.gov/pubmed/37620362
http://dx.doi.org/10.1038/s41419-023-06038-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449923/
https://www.ncbi.nlm.nih.gov/pubmed/37620362
http://dx.doi.org/10.1038/s41419-023-06038-x

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