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S1PR-1/5 modulator RP-101074 shows beneficial effects in a model of central nervous system degeneration

INTRODUCTION: In multiple sclerosis (MS), chronic disability primarily stems from axonal and neuronal degeneration, a condition resistant to conventional immunosuppressive or immunomodulatory treatments. Recent research has indicated that selective sphingosine-1-phosphate receptor S1PR-1 and -5 modu...

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Detalles Bibliográficos
Autores principales:	Sindi, Mustafa, Hecker, Christina, Issberner, Andrea, Ruck, Tobias, Meuth, Sven G., Albrecht, Philipp, Dietrich, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450045/ https://www.ncbi.nlm.nih.gov/pubmed/37638037 http://dx.doi.org/10.3389/fimmu.2023.1234984

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