Dna2 removes toxic ssDNA-RPA filaments generated from meiotic recombination-associated DNA synthesis

During the repair of DNA double-strand breaks (DSBs), de novo synthesized DNA strands can displace the parental strand to generate single-strand DNAs (ssDNAs). Many programmed DSBs and thus many ssDNAs occur during meiosis. However, it is unclear how these ssDNAs are removed for the complete repair...

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Detalles Bibliográficos
Autores principales: Zhai, Binyuan, Zhang, Shuxian, Li, Bo, Zhang, Jiaming, Yang, Xuan, Tan, Yingjin, Wang, Ying, Tan, Taicong, Yang, Xiao, Chen, Beiyi, Tian, Zhongyu, Cao, Yanding, Huang, Qilai, Gao, Jinmin, Wang, Shunxin, Zhang, Liangran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450173/
https://www.ncbi.nlm.nih.gov/pubmed/37351599
http://dx.doi.org/10.1093/nar/gkad537

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