Ncs2* mediates in vivo virulence of pathogenic yeast through sulphur modification of cytoplasmic transfer RNA

Fungal pathogens threaten ecosystems and human health. Understanding the molecular basis of their virulence is key to develop new treatment strategies. Here, we characterize NCS2*, a point mutation identified in a clinical baker's yeast isolate. Ncs2 is essential for 2-thiolation of tRNA and th...

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Detalles Bibliográficos
Autores principales: Alings, Fiona, Scharmann, Karin, Eggers, Cristian, Böttcher, Bettina, Sokołowski, Mikołaj, Shvetsova, Ekaterina, Sharma, Puneet, Roth, Joël, Rashiti, Leon, Glatt, Sebastian, Brunke, Sascha, Leidel, Sebastian A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450187/
https://www.ncbi.nlm.nih.gov/pubmed/37462076
http://dx.doi.org/10.1093/nar/gkad564

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