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Extension of mRNA poly(A) tails and 3′UTRs during neuronal differentiation exhibits variable association with post-transcriptional dynamics

Differentiation of neural progenitor cells into mature neuronal phenotypes relies on extensive temporospatial coordination of mRNA expression to support the development of functional brain circuitry. Cleavage and polyadenylation of mRNA has tremendous regulatory capacity through the alteration of mR...

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Detalles Bibliográficos
Autores principales: Kiltschewskij, Dylan J, Harrison, Paul F, Fitzsimmons, Chantel, Beilharz, Traude H, Cairns, Murray J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450200/
https://www.ncbi.nlm.nih.gov/pubmed/37293985
http://dx.doi.org/10.1093/nar/gkad499