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De novo transcriptome analysis of Dysoxylum binectariferum to unravel the biosynthesis of pharmaceutically relevant specialized metabolites

The tropical tree, D. binectariferum, is a prominent source of chromone alkaloid rohitukine, which is used in the semi-syntheses of anticancer molecules such as flavopiridol and P-276-00. The biosynthetic pathway of rohitukine or its derivatives is currently unknown in plants. Here, we explored chro...

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Detalles Bibliográficos
Autores principales: Kumara, Patel Mohana, Varun, Eranna, Sanjay, Joshi Renuka, Madhushree, Anchedoddi Hanumegowda, Thimmappa, Ramesha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450223/
https://www.ncbi.nlm.nih.gov/pubmed/37636089
http://dx.doi.org/10.3389/fpls.2023.1098987