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Piezoelectric signals of HAp and collagen with different glucose concentrations: A method for diabetes detection
Piezoelectric signals were obtained from samples based on hydroxyapatite (HAp) and collagen (C) containing different glucose (G) concentrations. HAp was obtained by coprecipitation using Ca(2+) and HPO(4)(2−) as precursor ions in solution. C and G were added at the beginning of the coprecipitation m...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450290/ https://www.ncbi.nlm.nih.gov/pubmed/37141710 http://dx.doi.org/10.1177/00368504231169714 |
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author | Vargas, Susana Rodriguez-Vargas, Rogelio G. Quintanilla, Francisco Rodriguez, Rogelio |
author_facet | Vargas, Susana Rodriguez-Vargas, Rogelio G. Quintanilla, Francisco Rodriguez, Rogelio |
author_sort | Vargas, Susana |
collection | PubMed |
description | Piezoelectric signals were obtained from samples based on hydroxyapatite (HAp) and collagen (C) containing different glucose (G) concentrations. HAp was obtained by coprecipitation using Ca(2+) and HPO(4)(2−) as precursor ions in solution. C and G were added at the beginning of the coprecipitation method during the HAp growth. The presence of glucose in HAp and collagen samples drastically reduces the voltage amplitudes and considerably increases the relaxation times of the piezoelectric signals. HAp and collagen are the main constituents of bone, muscle, etc., then, it is possible to use piezoelectric technology for local and early detection of high glucose concentrations: small pressures applied by electrodes or by actuators placed in appropriate places on the body to establish a background concentration and, from this, to determine regions of the body with high local glucose concentrations: weak signals and large relaxation times are associated with a diminishing in the sensitivity, and are indicative of the presence of regions of abnormally high glucose concentrations. |
format | Online Article Text |
id | pubmed-10450290 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-104502902023-08-26 Piezoelectric signals of HAp and collagen with different glucose concentrations: A method for diabetes detection Vargas, Susana Rodriguez-Vargas, Rogelio G. Quintanilla, Francisco Rodriguez, Rogelio Sci Prog Original Manuscript Piezoelectric signals were obtained from samples based on hydroxyapatite (HAp) and collagen (C) containing different glucose (G) concentrations. HAp was obtained by coprecipitation using Ca(2+) and HPO(4)(2−) as precursor ions in solution. C and G were added at the beginning of the coprecipitation method during the HAp growth. The presence of glucose in HAp and collagen samples drastically reduces the voltage amplitudes and considerably increases the relaxation times of the piezoelectric signals. HAp and collagen are the main constituents of bone, muscle, etc., then, it is possible to use piezoelectric technology for local and early detection of high glucose concentrations: small pressures applied by electrodes or by actuators placed in appropriate places on the body to establish a background concentration and, from this, to determine regions of the body with high local glucose concentrations: weak signals and large relaxation times are associated with a diminishing in the sensitivity, and are indicative of the presence of regions of abnormally high glucose concentrations. SAGE Publications 2023-05-04 /pmc/articles/PMC10450290/ /pubmed/37141710 http://dx.doi.org/10.1177/00368504231169714 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Manuscript Vargas, Susana Rodriguez-Vargas, Rogelio G. Quintanilla, Francisco Rodriguez, Rogelio Piezoelectric signals of HAp and collagen with different glucose concentrations: A method for diabetes detection |
title | Piezoelectric signals of HAp and collagen with different glucose concentrations: A method for diabetes detection |
title_full | Piezoelectric signals of HAp and collagen with different glucose concentrations: A method for diabetes detection |
title_fullStr | Piezoelectric signals of HAp and collagen with different glucose concentrations: A method for diabetes detection |
title_full_unstemmed | Piezoelectric signals of HAp and collagen with different glucose concentrations: A method for diabetes detection |
title_short | Piezoelectric signals of HAp and collagen with different glucose concentrations: A method for diabetes detection |
title_sort | piezoelectric signals of hap and collagen with different glucose concentrations: a method for diabetes detection |
topic | Original Manuscript |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450290/ https://www.ncbi.nlm.nih.gov/pubmed/37141710 http://dx.doi.org/10.1177/00368504231169714 |
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