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CFD analysis on blood flow inside a symmetric stenosed artery: Physiology of a coronary artery disease

This research article interprets the computational fluid dynamics analysis on blood flow inside a symmetric stenosed artery. The current problem models the blood flow inside the left coronary artery as having a symmetric stenosis in the central region. A comprehensive physiological examination of co...

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Autores principales: Akhtar, Salman, Hussain, Zahir, Nadeem, Sohail, Najjar, I. M. R, Sadoun, A.M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450296/
https://www.ncbi.nlm.nih.gov/pubmed/37292014
http://dx.doi.org/10.1177/00368504231180092
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author Akhtar, Salman
Hussain, Zahir
Nadeem, Sohail
Najjar, I. M. R
Sadoun, A.M
author_facet Akhtar, Salman
Hussain, Zahir
Nadeem, Sohail
Najjar, I. M. R
Sadoun, A.M
author_sort Akhtar, Salman
collection PubMed
description This research article interprets the computational fluid dynamics analysis on blood flow inside a symmetric stenosed artery. The current problem models the blood flow inside the left coronary artery as having a symmetric stenosis in the central region. A comprehensive physiological examination of coronary artery disease is numerically evaluated by using the computational fluid dynamics toolbox Open-Field Operation And Manipulation. There are no assumptions of mild stenosis taken into account since the considered stenosis has an exactly measured length, height and position, etc. The blood flow problem is modeled for the non-Newtonian Casson fluid with unsteady, laminar, and incompressible flow assumptions. The underlying problem is solved numerically in its dimensional form. A thorough graphical analysis is provided on the blood flow simulations, pressure profile, velocity line graphs, pressure line graphs, and streamlines for the left coronary artery having a symmetric stenosis formation. The considered artery is divided into three sections, i.e. pre-stenosis, post-stenosis, and stenosis region, and the velocity and pressure line graphs are plotted for these considered regions. The graphical illustrations provide a detailed analysis of how the blood flow is affected inside the left coronary artery due to coronary artery disease. These pre- and post-stenosis velocity line graphs reveal two intriguing results: In the pre-stenosis zone, the velocity increases with increasing axial coordinate length, whereas in the post-stenosis region, the velocity decreases with rising axial coordinate length. It is evident that as the flow moves toward the stenosis region, the flow profile rises; yet, after passing through the stenosis zone, the flow profile begins to fall as the flow moves away from the stenosis region.
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spelling pubmed-104502962023-08-26 CFD analysis on blood flow inside a symmetric stenosed artery: Physiology of a coronary artery disease Akhtar, Salman Hussain, Zahir Nadeem, Sohail Najjar, I. M. R Sadoun, A.M Sci Prog Medicine & Health Sciences This research article interprets the computational fluid dynamics analysis on blood flow inside a symmetric stenosed artery. The current problem models the blood flow inside the left coronary artery as having a symmetric stenosis in the central region. A comprehensive physiological examination of coronary artery disease is numerically evaluated by using the computational fluid dynamics toolbox Open-Field Operation And Manipulation. There are no assumptions of mild stenosis taken into account since the considered stenosis has an exactly measured length, height and position, etc. The blood flow problem is modeled for the non-Newtonian Casson fluid with unsteady, laminar, and incompressible flow assumptions. The underlying problem is solved numerically in its dimensional form. A thorough graphical analysis is provided on the blood flow simulations, pressure profile, velocity line graphs, pressure line graphs, and streamlines for the left coronary artery having a symmetric stenosis formation. The considered artery is divided into three sections, i.e. pre-stenosis, post-stenosis, and stenosis region, and the velocity and pressure line graphs are plotted for these considered regions. The graphical illustrations provide a detailed analysis of how the blood flow is affected inside the left coronary artery due to coronary artery disease. These pre- and post-stenosis velocity line graphs reveal two intriguing results: In the pre-stenosis zone, the velocity increases with increasing axial coordinate length, whereas in the post-stenosis region, the velocity decreases with rising axial coordinate length. It is evident that as the flow moves toward the stenosis region, the flow profile rises; yet, after passing through the stenosis zone, the flow profile begins to fall as the flow moves away from the stenosis region. SAGE Publications 2023-06-08 /pmc/articles/PMC10450296/ /pubmed/37292014 http://dx.doi.org/10.1177/00368504231180092 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Medicine & Health Sciences
Akhtar, Salman
Hussain, Zahir
Nadeem, Sohail
Najjar, I. M. R
Sadoun, A.M
CFD analysis on blood flow inside a symmetric stenosed artery: Physiology of a coronary artery disease
title CFD analysis on blood flow inside a symmetric stenosed artery: Physiology of a coronary artery disease
title_full CFD analysis on blood flow inside a symmetric stenosed artery: Physiology of a coronary artery disease
title_fullStr CFD analysis on blood flow inside a symmetric stenosed artery: Physiology of a coronary artery disease
title_full_unstemmed CFD analysis on blood flow inside a symmetric stenosed artery: Physiology of a coronary artery disease
title_short CFD analysis on blood flow inside a symmetric stenosed artery: Physiology of a coronary artery disease
title_sort cfd analysis on blood flow inside a symmetric stenosed artery: physiology of a coronary artery disease
topic Medicine & Health Sciences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450296/
https://www.ncbi.nlm.nih.gov/pubmed/37292014
http://dx.doi.org/10.1177/00368504231180092
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