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Two-year follow-up of a thyroid cartilage metastasis from prostate cancer: A case report
Few case reports describe metastatic prostate cancer to the thyroid cartilage. While earlier reports identified the metastatic lesions upon developing symptoms, more recent ones have detected them via prostate-specific membrane antigen positron emission tomography (PSMA PET). Herein, we report the c...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450348/ https://www.ncbi.nlm.nih.gov/pubmed/37636542 http://dx.doi.org/10.1016/j.radcr.2023.07.071 |
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author | Kobeissi, Jana M. Youssef, Bassem Mobayed, Tala |
author_facet | Kobeissi, Jana M. Youssef, Bassem Mobayed, Tala |
author_sort | Kobeissi, Jana M. |
collection | PubMed |
description | Few case reports describe metastatic prostate cancer to the thyroid cartilage. While earlier reports identified the metastatic lesions upon developing symptoms, more recent ones have detected them via prostate-specific membrane antigen positron emission tomography (PSMA PET). Herein, we report the case of a patient with metastatic castrate-resistant prostate cancer and a PSMA PET-detected lesion in the thyroid cartilage. Over the course of 2 years, he received multiple lines of chemotherapy and hormonal therapy, and his overall disease status fluctuated — some nodal and bony metastases resolved while others appeared anew. His thyroid cartilage lesion, however, slowly progressed in a consistent fashion with increasing uptake on successive PSMA PET images. Apart from mild dysphonia, the patient remained to be asymptomatic from this lesion, and no local therapies were used. To our knowledge, this is the first close follow-up of prostate cancer metastatic to the thyroid cartilage, shedding light on the course of such lesions and helping answer management-related questions, which are particularly relevant as more occult metastases are discovered in the PSMA PET era. |
format | Online Article Text |
id | pubmed-10450348 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-104503482023-08-26 Two-year follow-up of a thyroid cartilage metastasis from prostate cancer: A case report Kobeissi, Jana M. Youssef, Bassem Mobayed, Tala Radiol Case Rep Case Report Few case reports describe metastatic prostate cancer to the thyroid cartilage. While earlier reports identified the metastatic lesions upon developing symptoms, more recent ones have detected them via prostate-specific membrane antigen positron emission tomography (PSMA PET). Herein, we report the case of a patient with metastatic castrate-resistant prostate cancer and a PSMA PET-detected lesion in the thyroid cartilage. Over the course of 2 years, he received multiple lines of chemotherapy and hormonal therapy, and his overall disease status fluctuated — some nodal and bony metastases resolved while others appeared anew. His thyroid cartilage lesion, however, slowly progressed in a consistent fashion with increasing uptake on successive PSMA PET images. Apart from mild dysphonia, the patient remained to be asymptomatic from this lesion, and no local therapies were used. To our knowledge, this is the first close follow-up of prostate cancer metastatic to the thyroid cartilage, shedding light on the course of such lesions and helping answer management-related questions, which are particularly relevant as more occult metastases are discovered in the PSMA PET era. Elsevier 2023-08-14 /pmc/articles/PMC10450348/ /pubmed/37636542 http://dx.doi.org/10.1016/j.radcr.2023.07.071 Text en © 2023 The Authors. Published by Elsevier Inc. on behalf of University of Washington. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Kobeissi, Jana M. Youssef, Bassem Mobayed, Tala Two-year follow-up of a thyroid cartilage metastasis from prostate cancer: A case report |
title | Two-year follow-up of a thyroid cartilage metastasis from prostate cancer: A case report |
title_full | Two-year follow-up of a thyroid cartilage metastasis from prostate cancer: A case report |
title_fullStr | Two-year follow-up of a thyroid cartilage metastasis from prostate cancer: A case report |
title_full_unstemmed | Two-year follow-up of a thyroid cartilage metastasis from prostate cancer: A case report |
title_short | Two-year follow-up of a thyroid cartilage metastasis from prostate cancer: A case report |
title_sort | two-year follow-up of a thyroid cartilage metastasis from prostate cancer: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450348/ https://www.ncbi.nlm.nih.gov/pubmed/37636542 http://dx.doi.org/10.1016/j.radcr.2023.07.071 |
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